From: Serum protein signature of coronary artery disease in type 2 diabetes mellitus
Variables | Control (n = 26) | T2DM (n = 53) | CAD (n = 25) | T2DM_CAD (n = 26) |
---|---|---|---|---|
Age (years) | 44.3 ± 9.4 | 46.5 ± 8.5 | 48.8 ± 6.6 | 51.2 ± 8.2 |
Gender (male/female) | 15/11 | 28/25 | 24/1 | 23/3 |
BMI | 25.30 (22.31–28.30) | 26.5 (23.5–29.9) | 25.0 (22.6–26.7) | 25.3 (22.7–26.7) |
Systolic BP (mmHg) | 124.3 (121.0–130.6) | 136.2 (127.5–149.6) | 133.0 (123.8–139.0) | 133.0 (112.7–145.4) |
Diastolic BP (mmHg) | 81.3 (77.6–84.0) | 82.8 (78.2–93.0) | 80.5 (74.7–85.7) | 82.8 (73.4–89.3) |
HbA1C (%) | 5.4 (5.2–5.7) | 7.9 (7.2–9.1)a | 5.4 (5.2–5.6) | 8.6 (7.8–9.4)a, b |
FBS (mg/dl) | 97.0 (88.0–107.0) | 188.0 (150.0–239.2)a | 97.5(83.7–109.7) | 191.5(154.8–256.5)a, b |
Creatinine (mg/dl) | 0.8 (0.7–0.9) | 0.9 (0.7–1.0) | 0.9 (0.8–1.0) | 1.0 (0.8–1.2) |
eGFR (ml/min/1.73m2) | 100 (85–117) | 92.5 (80.2–109.0) | 91.5 (81.2–105.2) | 80.5 (66.7–99.0) |
Uric acid (mg/dl) | 4.2 (3.5–5.7) | 4.0 (3.3–4.8) | 4.6 (4.1–6.1) | 4.3 (3.4–5.5) |
CK-MB (mg/dl) | 20 (16.0–24.0) | 17.0 (13.7–22.0) | 22.5 (19.5–26.7) | 22.5 (20.0–29.5) |
Smoking history (yes/no) | 4/22 | 13/40 | 10/15 | 16/10 |
Alcoholic history (yes/no) | 7/19 | 14/39 | 8/17 | 19/6 |
FRS (%) | 0.9 (0.5–3.8) | 1.5 (0.3–6.7) | 5.2 (2.15–9.3) | 5.3 (2.7–10.7)a |
ASCVD (%) | 1.9 (0.9–3.9) | 4.0 (2.4–16.4)a | 10 (3–15.1)a | 15.4 (9.3–22.2)a |
Diabetic duration (years) | – | 2 (1–4) | – | 2 (1–5) |
Hypertension history | – | 25 | 16 | 14 |
Patients were on hypertensive drugs | – | 18 | 13 | 14 |
Patients were on anti-diabetes medication | – | 34 | – | 17 |
Patients were on anti-platelet and statin therapy | – | – | 25 | 26 |