From: FGFR1 expression defines clinically distinct subtypes in pancreatic cancer
P value | HR | Univariate Analysis | P value | HR | Multivariate analysis | |||
---|---|---|---|---|---|---|---|---|
95.0% CI for HR | 95.0% CI for HR | |||||||
Lower | Upper | Lower | upper | |||||
Age, years (≥ 60 vs. < 60) | 0.016 | 1.451 | 1.073 | 1.961 | 0.008 | 1.587 | 1.130 | 2.230 |
Gender | 0.235 | 1.191 | 0.892 | 1.591 | ||||
Tumor size, cm (≥ 2 vs. < 2) | 0.241 | 1.534 | 0.751 | 3.135 | ||||
Differentiation (well/moderate vs. poor) | 0.076 | 1.428 | 0.964 | 2.115 | ||||
Extension (confined vs. peripancreatic soft tissue) | 0.061 | 1.898 | 0.970 | 3.714 | ||||
Bile duct invasion (absent vs. present) | 0.009 | 1.469 | 1.099 | 1.963 | 0.002 | 1.657 | 1.211 | 2.269 |
Duodenum invasion (absent vs. present) | 0.074 | 1.303 | 0.975 | 1.742 | ||||
Lymphovascular invasion (absent vs. present) | 0.011 | 1.455 | 1.088 | 1.944 | 0.098 | 1.320 | .950 | 1.834 |
Perineural invasion (absent vs. present) | 0.086 | 1.403 | .953 | 2.064 | ||||
Lymph node metastasis (absent vs. present) | < 0.001 | 2.495 | 1.811 | 3.436 | < 0.0001 | 2.360 | 1.665 | 3.344 |
Tumor stagea | 0.059 | 1.382 | 0.988 | 1.933 | ||||
FGFR1 (positive vs. negative) | 0.003 | 0.590 | 0.415 | 0.839 | 0.035 | 0.677 | 0.471 | 0.972 |