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Table 4 Multivariate survival analyses of prognostic factors associated with OS and DFS for OSCC

From: Preoperative systemic immune-inflammation index predicts prognosis of patients with oral squamous cell carcinoma after curative resection

Variables

OS

DFS

HR [95% CI]ª

Pª

HR [95% CI]ª

Pª

Training cohort

 SII (≥ 484.5, < 484.5)

3.887 (1.358–11.126)

0.011

2.814 (1.242–6.375)

0.013

 NLR (≥ 2.9, < 2.9)

3.114 (1.148–8.446)

0.026

2.328 (1.000–5.422)

0.050

 PLR (≥ 170.2, < 170.2)

5.678 (2.130–15.135)

0.001

3.318 (1.414–7.788)

0.006

Validation cohort

 SII (≥ 484.5, < 484.5)

2.188 (1.326–3.610)

0.002

2.322 (1.444–3.732)

0.001

 NLR (≥ 2.9, < 2.9)

1.982 (1.150–3.416)

0.014

2.015 (1.204–3.373)

0.008

 PLR (≥ 170.2, < 170.2)

2.697 (1.628–4.466)

< 0.001

2.496 (1.538–4.050)

< 0.001

Combined cohort

 SII (≥ 484.5, < 484.5)

2.885 (1.845–4.511)

< 0.001

2.767 (1.842–4.157)

< 0.001

 NLR (≥ 2.9, < 2.9)

2.458 (1.547–3.903)

< 0.001

2.305 (1.499–3.543)

< 0.001

 PLR (≥ 170.2, < 170.2)

3.203 (2.071–4.954)

< 0.001

2.600 (1.727–3.912)

< 0.001

  1. HR hazard ratio, CI confidence interval
  2. ªAdjusted for age, gender, smoking, alcohol use, tumor size, pathological grade, cervical nodal metastasis, clinical stage in logistic regression models