|
Training cohort
|
|
Age (> 60, ≤ 60)
|
0.991 (0.395–2.485)
|
0.985
|
1.223 (0.559–2.676)
|
0.614
|
|
Gender (male, female)
|
1.344 (0.536–3.369)
|
0.529
|
2.067 (0.919–4.650)
|
0.079
|
|
Smoking (yes, no)
|
0.570 (0.207–1.568)
|
0.276
|
0.983 (0.467–2.068)
|
0.983
|
|
Alcohol use (yes, no)
|
0.832 (0.278–2.488)
|
0.742
|
1.610 (0.752–3.445)
|
0.220
|
|
Tumor size (T3–T4, T1–T2)
|
3.772 (1.561–9.117)
|
0.003
|
2.713 (1.322–5.566)
|
0.006
|
|
Pathological grade (II–III, I)
|
1.691 (0.704–4.063)
|
0.240
|
1.466 (0.715–3.004)
|
0.296
|
|
Cervical nodal metastasis (N+, N0)
|
1.653 (0.600–4.550)
|
0.331
|
2.219 (1.012–4.869)
|
0.047
|
|
Clinical stage (III–IV, I–II)
|
2.214 (0.921–5.325)
|
0.076
|
2.634 (1.279–5.422)
|
0.009
|
|
SII (≥ 484.5, < 484.5)
|
5.089 (2.027–12.775)
|
0.001
|
3.309 (1.609–6.805)
|
0.001
|
|
NLR (≥ 2.9, < 2.9)
|
4.270 (1.775–10.271)
|
0.001
|
3.031 (1.456–6.312)
|
0.003
|
|
PLR (≥ 170.2, < 170.2)
|
4.493 (1.859–10.854)
|
0.001
|
2.397 (1.096–5.242)
|
0.029
|
|
Validation cohort
|
|
Age (> 60, ≤ 60)
|
1.001 (0.607–1.651)
|
0.996
|
0.974 (0.609–1.559)
|
0.912
|
|
Gender (male, female)
|
1.124 (0.690–1.833)
|
0.639
|
1.071 (0.676–1.698)
|
0.769
|
|
Smoking (Yes, No)
|
0.779 (0.416–1.458)
|
0.779
|
0.882 (0.459–1.473)
|
0.510
|
|
Alcohol use (Yes, No)
|
1.143 (0.610–2.141)
|
0.677
|
1.100 (0.603–2.005)
|
0.757
|
|
Tumor size (T3–T4, T1–T2)
|
1.073 (0.582–1.976)
|
0.821
|
1.084 (0.602–1.954)
|
0.787
|
|
Pathological grade (II–III, I)
|
2.039 (1.247–3.334)
|
0.005
|
1.789 (1.125–2.844)
|
0.014
|
|
Cervical nodal metastasis (N+, N0)
|
1.137 (0.663–1.949)
|
0.641
|
1.116 (0.662–1.883)
|
0.680
|
|
Clinical stage (III–IV, I–II)
|
1.209 (0.733–1.994)
|
0.457
|
1.148 (0.707–1.864)
|
0.576
|
|
SII (≥ 484.5, < 484.5)
|
2.348 (1.439–3.832)
|
0.001
|
2.431 (1.525–3.876)
|
< 0.001
|
|
NLR (≥ 2.9, < 2.9)
|
2.101 (1.263–3.496)
|
0.004
|
2.072 (1.275–3.369)
|
0.003
|
|
PLR (≥ 170.2, < 170.2)
|
2.633 (1.610–4.307)
|
< 0.001
|
2.423 (1.508–3.893)
|
< 0.001
|
|
Combined cohort
|
|
Age (> 60, ≤ 60)
|
0.971 (0.626–1.507)
|
0.897
|
0.998 (0.669–1.490)
|
0.992
|
|
Gender (male, female)
|
1.090 (0.710–1.674)
|
0.693
|
1.192 (0.805–1.764)
|
0.380
|
|
Smoking (yes, no)
|
0.598 (0.351–1.018)
|
0.058
|
0.750 (0.477–1.177)
|
0.210
|
|
Alcohol use (yes, no)
|
0.942 (0.547–1.623)
|
0.830
|
1.143 (0.718–1.819)
|
0.573
|
|
Tumor size (T3–T4, T1–T2)
|
1.439 (0.897–2.309)
|
0.131
|
1.387 (0.898–2.142)
|
0.140
|
|
Pathological grade (II–III, I)
|
1.913 (1.248–2.933)
|
0.003
|
1.609 (1.093–2.369)
|
0.016
|
|
Cervical nodal metastasis (N + , N0)
|
1.337 (0.833–2.145)
|
0.229
|
1.410 (0.915–2.172)
|
0.119
|
|
Clinical stage (III–IV, I–II)
|
1.437 (0.935–2.208)
|
0.098
|
1.462 (0.987–2.166)
|
0.058
|
|
SII (≥ 484.5, < 484.5)
|
3.037 (1.973–4.673)
|
< 0.001
|
2.801 (1.896–4.138)
|
< 0.001
|
|
NLR (≥ 2.9, < 2.9)
|
2.587 (1.672–4.005)
|
< 0.001
|
2.378 (1.588–3.562)
|
< 0.001
|
|
PLR (≥ 170.2, < 170.2)
|
3.250 (2.116–4.993)
|
< 0.001
|
2.545 (1.703–3.803)
|
< 0.001
|
