Journal of Translational Medicine

Table 2 Associations between SII and multiple clinicopathological parameters in OSCC

From: Preoperative systemic immune-inflammation index predicts prognosis of patients with oral squamous cell carcinoma after curative resection

Variable	SII
	Training cohort			Validation cohort			Combined cohort
	< 484.5	≥ 484.5	P	< 484.5	≥ 484.5	P	< 484.5	≥ 484.5	P
No. of patients	96	42		105	66		201	108
Age (y)
≤ 60	36	11	0.197	38	27	0.536	74	38	0.776
> 60	60	31		67	39		127	70
Gender
Male	53	28	0.208	51	39	0.180	104	67	0.083
Female	43	14		54	27		97	41
Smoking
No	61	28	0.724	83	50	0.614	144	78	0.914
Yes	35	14		22	16		57	30
Alcohol use
No	70	34	0.313	90	51	0.158	160	85	0.853
Yes	26	8		15	15		41	23
Tumor size
T1–T2	78	25	0.007	88	47	0.049	166	72	0.002
T3–T4	18	17		17	19		35	36
Pathological grade
I	61	22	0.218	63	32	0.140	124	54	0.047
II–III	35	20		42	34		77	54
Cervical nodal metastasis
N0	78	34	0.967	73	48	0.654	151	82	0.876
N+	18	8		32	18		50	26
Clinical stage
I–II	65	26	0.508	65	35	0.252	130	61	0.157
III–IV	31	16		40	31		71	47

The italic values in the table denotes P-values less than 0.05 with statistical significance

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