Enhanced AZIN1 RNA editing and overexpression of its regulatory enzyme ADAR1 are important prognostic biomarkers in gastric cancer

Table 1 Correlation between clinicopathological Variables and AZIN1 RNA editing and ADAR1 expression in Gastric Cancer patients

Variable	n	AZIN1 RNA editing		P value	ADAR1 expression		P value
Variable	n	High (n = 56)	Low (n = 84)	P value	High (n = 78)	Low (n = 62)	P value
Gender
Male	110	44	66	1	62	48	0.77
Female	30	12	18		16	14
Age (year)
69≥^a	72	31	41	0.45	42	30	0.52
>69	68	25	43		36	32
Histological type
Intestinal type	69	29	40	0.63	41	28	0.39
Diffuse type	71	27	44		37	34
Pathological T category
pT1/2	50	14	36	0.031*	24	26	0.17
pT3/4	90	42	48		54	36
Vessel invasion
Present	111	43	68	0.55	62	49	0.95
Absent	29	13	16		16	13
Lymphovascular invasion
Present	128	52	76	0.62	74	54	0.1
Absent	12	4	8		4	8
Lymph node metastasis
N0	43	11	32	0.021*	18	25	0.029*
N1	97	45	52		60	37
Peritoneal metastasis
P0	117	43	74	0.08	61	56	0.06
P1	23	13	10		17	6
Distant metastasis
M0	101	39	62	0.59	49	52	0.006*
M1	39	17	22		29	10
UICC TNM classification
Stage I	23	5	18	0.028*	11	12	0.004*
Stage II	39	12	27		15	24
Stage III	39	22	17		23	16
Stage IV	39	17	22		29	10

ISSN: 1479-5876