Fig. 1

Dysregulation of AZIN1 RNA editing and ADAR1 expression status in tissues from GC patients. a AZIN1 RNA editing levels (left) and ADAR1 expression levels (right) were significantly increased in primary cancer tissues compared with adjacent normal mucosa. b ROC curve analysis for AZIN1 RNA editing levels (left) and ADAR1 expression levels (right) for distinguishing between GC and normal gastric mucosa. AZIN1 RNA editing levels and ADAR1 expression levels could distinguish GC tissues from normal gastric mucosa with area under the curve values of 0.75 (95% CI 0.69–0.8), 0.66 (95% CI 0.6–0.84), respectively. c Scattergrams of AZIN1 RNA editing levels (left) and ADAR1 expression levels (right) according to UICC classification in gastric cancer patients