Table 1 Inclusion and exclusion criteria

Inclusion criteria

 Men or women aged 18–70

 Diagnosis of knee osteoarthritis

 Kellgren–Lawrence (KL) classification of grade II or III OA severity

Exclusion criteria

 BMI > 30

 Knee flexion < 110º

 Knee varus > 12º

 Knee valgus > 15º

 Instability as demonstrated by > 2 mm translation upon physical examination

 Knee flexion contracture greater than 15º

 History of ACL reconstruction or evidence of complete or partial ACL disruption

 Knee Society Score < 65

 History of septic arthritis within the last 5 years

 History of knee surgery within the last 6 months

 Currently experiencing low back pain with radiculopathy

 History of immunosuppressive disease or chemotherapy in last 5 years

 History of systemic neurological disease

 Positive HIV serology or chronic hepatitis