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Table 4 Compounds identified as potential treatment options for EMI based on CMap analysis

From: Circular RNA regulatory network reveals cell–cell crosstalk in acute myeloid leukemia extramedullary infiltration

CMap names Enrichment score Dose (µM) Cell Up scores Down scores
LY-294002 − 0.969 10 PC3 − 0.228 0.284
LY-294002 − 0.968 10 PC3 − 0.307 0.205
LY-294002 − 0.884 10 HL60 − 0.227 0.24
LY-294002 − 0.859 10 HL60 − 0.252 0.202
Trichostatin A − 0.847 1 HL60 − 0.229 0.219
LY-294002 − 0.833 10 HL60 − 0.319 0.122
LY-294002 − 0.809 10 HL60 − 0.212 0.215
SB-202190 − 0.801 1 MCF7 − 0.149 0.275
  1. CMap connectivity map