Fig. 2

Heatmap of circRNA in EMI and non-EMI AML samples. The overlap patterns were significantly different for circRNAs in the EMI and non-EMI AML groups versus those of healthy volunteers. There were 253 significantly upregulated (a) and 259 downregulated (b) circRNAs in the EMI versus the non-EMI AML group (purple area). Eighty-two significantly upregulated (a) and 27 downregulated (b) circRNAs were found among all AML patients (EMI and non-EMI AML) versus healthy volunteers. Finally, 171 significantly upregulated (a) and 232 downregulated (b) circRNAs were likely responsible for EMI after exclusion of those responsible for AML