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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Circular RNA regulatory network reveals cell–cell crosstalk in acute myeloid leukemia extramedullary infiltration

Fig. 1

Microarray information of differential circRNA profiles from EMI and non-EMI AML samples. a The percentage of significantly differentially expressed circRNAs derived from different genomic loci (exonic, intronic, antisense, intergenic, and sense overlapping). b Volcano plot. X-axis: the fold change expressed as log2; Y-axis: p-value expressed as − log10. The vertical green lines correspond to 2.0-fold up- and downregulation, and the horizontal green line represents a p-value of 0.05. The red points in the plot represent circRNAs that were significantly differentially expressed. c Hierarchical clustering of circRNA expression data. Samples are classified into different groups based on their expression levels, revealing distinguishable circRNA expression profiling among the EMI and non-EMI AML samples

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