Table 1 Correlation between paralogous group 13 (HOXA13, HOXB13, HOXC13, HOXD13) and HOTAIR expression and main clinical features of CRC patients
From: Posterior HOX genes and HOTAIR expression in the proximal and distal colon cancer pathogenesis
| Â | HOXA13 | p-value | HOXB13 | p-value | HOXC13 | p-value | HOXD13 | p-value | HOTAIR | p value | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Low | High | Low | High | Low | High | Low | High | Low | High | ||||||
Gender | |||||||||||||||
 M | 24 (29.6) | 19 (23.5) | 1 | 19 (23.2) | 25 (30.5) | 0.081 | 24 (29.3) | 20 (24.4) | 1 | 27 (32.9) | 17 (21) | 1 | 8 (10.0) | 36 (45.0) | 0.78 |
 F | 21 (25.9) | 17 (21) | 24 (29.3) | 14 (17.1) | 21 (25.6) | 17 (20.7) | 23 (29.1) | 15 (20.8) | 8 (10.0) | 28 (35.0) | |||||
Age | |||||||||||||||
 < 50 | 18 (22.2) | 18 (22.2) | 0.5 | 23 (28.0) | 13 (15.9) | 0.078 | 18 (22) | 18 (22) | 0.5 | 20 (24.4) | 16 (19.5) | 0.494 | 11 (23.9) | 12 | 0.057 |
 > 50 | 27 (33.3) | 18 (22.2) | 20 (24.4) | 26 (31.7) | 27 (32.9) | 19 (23.2) | 30 (36;6) | 16 (19.5) | 4 (8.7) | 19 (41.3) | |||||
T | |||||||||||||||
 T1/T2 | 15 (19.2) | 16 (20.5) | 0.36 | 17 (21.5) | 14 (17.7) | 1 | 15 (19.2) | 16 (20.3) | 0.25 | 19 (24.1) | 12 (15.2) | 1 | 6 (7.8) | 25 (32.5) | 0.04 |
 T3/T4 | 28 (35.9) | 19 (24.4) | 26 (32.9) | 22 (27.8) | 30 (38) | 18 (22.8) | 29 (36.7) | 19 (24.1) | 10 (13.0) | 36 (46.8) | |||||
Grade | |||||||||||||||
 G1 | 1 (1.2) | 2 (2.5) | 0.855 | 2 (2.4) | 1 (1.2) | 1 | 2 (2.4) | 1 (1.2) | 1 | 3 (3.7) | 0 | 0.307 | 2 (2.5) | 1 (1.25) | 1 |
 G2 | 41 (50.6) | 32 (39.5) | 38 (46.3) | 36 (43.9) | 40 (48.8) | 34 (41.5) | 45 (54.9) | 29 (35.4) | 40 (50) | 32 (40) | |||||
 G3 | 3 (3.7) | 2 (2.5) | 3 (3.7) | 2 (2.4) | 3 (3.7) | 2 (2.4) | 2 (2.5) | 3 (3.7) | 3 (3.8) | 2 (2.5) | |||||
N | |||||||||||||||
 N0 | 31 (41.9) | 17 (20.7) | 0.134 | 32 (43.2) | 16 (21.6) | 0.003 | 32 (44.4) | 16 (21.6) | 0.051 | 31 (41.9) | 17 (20.7) | 0.456 | 14 (19.4) | 33 (45.5) | 0.04 |
 N+ | 11 (15.1) | 14 (19.2) | 8 (10.8) | 18 (24.3) | 11 (14.9) | 15 (20.3) | 14 (18.9) | 12 (16.2) | 2 (2.8) | 23 (31.9) | |||||