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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: l-Fucose ameliorates high-fat diet-induced obesity and hepatic steatosis in mice

Fig. 1

Metagenomic analysis showed that HFD altered the cecal microbial function. a Principal coordinate analysis (PCoA) based on metagenomic analysis for cecal content DNA of NC and HFD mice (n = 4). b Volcano plot analysing genomic abundance in the HFD group compared with those in the NC group. The x-coordinate is the (log) fold-change (FC) and the y-coordinate is the −log10 of the p-value from a t-test (n = 4). c Relative genomic abundance of alpha-l-fucosidase (fuca) in the cecal content of mice (n = 4). d Alpha-l-fucosidase (FUCA) levels in human stool samples (n = 8–9). Data are expressed as mean ± SEM. *p < 0.05, two-tailed Student’s t test, HFD group vs NC group

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