Table 5 Meta-analysis of HLA-DQB1 alleles associated with hepatitis B virus spontaneous clearance
From: The roles of HLA-DQB1 gene polymorphisms in hepatitis B virus infection
HLA-DQB1* | N | Heterogeneity | Overall relationship | |||
|---|---|---|---|---|---|---|
I2 (%) | P | Model | OR (95% CI) | P | ||
02:01 | 6 | 47 | 0.09 | F | 0.77 (0.60–0.98) | 0.04 |
03:01 | 5 | 82 | 0.0002 | R | 0.52 (0.25–1.06) | 0.07 |
03:02 | 5 | 56 | 0.09 | R | 1.34 (0.85–2.11) | 0.21 |
03:03 | 5 | 0 | 0.86 | F | 1.18 (0.93–1.51) | 0.17 |
04:01 | 5 | 0 | 0.69 | F | 1.16 (0.78–1.73) | 0.46 |
04:02 | 4 | 0 | 0.57 | F | 1.11 (0.59–2.10) | 0.75 |
05:01 | 6 | 0 | 0.65 | F | 1.04 (0.73–1.49) | 0.82 |
05:02 | 6 | 9 | 0.36 | F | 0.44 (0.27–0.70) | 0.0006 |
05:03 | 4 | 0 | 0.95 | F | 0.81 (0.50–1.33) | 0.41 |
06:01 | 4 | 40 | 0.17 | F | 0.77 (0.56–1.06) | 0.11 |
06:02 | 6 | 0 | 0.97 | F | 1.25 (0.97–1.61) | 0.09 |
06:03 | 3 | 0 | 0.45 | F | 1.20 (0.47–3.08) | 0.70 |
06:04 | 5 | 0 | 0.98 | F | 2.00 (1.07–3.74) | 0.03 |