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Table 5 Meta-analysis of HLA-DQB1 alleles associated with hepatitis B virus spontaneous clearance

From: The roles of HLA-DQB1 gene polymorphisms in hepatitis B virus infection

HLA-DQB1* N Heterogeneity Overall relationship
I2 (%) P Model OR (95% CI) P
02:01 6 47 0.09 F 0.77 (0.60–0.98) 0.04
03:01 5 82 0.0002 R 0.52 (0.25–1.06) 0.07
03:02 5 56 0.09 R 1.34 (0.85–2.11) 0.21
03:03 5 0 0.86 F 1.18 (0.93–1.51) 0.17
04:01 5 0 0.69 F 1.16 (0.78–1.73) 0.46
04:02 4 0 0.57 F 1.11 (0.59–2.10) 0.75
05:01 6 0 0.65 F 1.04 (0.73–1.49) 0.82
05:02 6 9 0.36 F 0.44 (0.27–0.70) 0.0006
05:03 4 0 0.95 F 0.81 (0.50–1.33) 0.41
06:01 4 40 0.17 F 0.77 (0.56–1.06) 0.11
06:02 6 0 0.97 F 1.25 (0.97–1.61) 0.09
06:03 3 0 0.45 F 1.20 (0.47–3.08) 0.70
06:04 5 0 0.98 F 2.00 (1.07–3.74) 0.03
  1. OR odds ratio, CI confidence interval, F fix effects model, R random effects model
  2. Italic values indicate significance of p value (p≤0.05)