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Table 2 SNPs main features of circadian genes tested in this study

From: Associations of clock genes polymorphisms with soft tissue sarcoma susceptibility and prognosis

Gene SNP ID Genotype Ctrls Cases P-val. Chr Region Residue Ref in cancer
CLOCK rs1801260 TT 323 92 0.21 4 3′-UTR   [10, 12, 13, 15, 16, 25, 27, 33, 34]
   TC 228 62      
   CC 56 8      
  rs3736544 GG 241 60 0.72 4 Exon Asn>Asn  
   GA 269 78      
   AA 95 24      
  rs3749474 CC 259 62 0.45 4 3′-UTR   [10, 15, 16, 33, 35]
   CT 266 80      
   TT 83 20      
  rs34897046 GG 566 149 0.60 4 Exon Ser>Cys  
   GC 40 13      
   CC 1 0      
NPAS2 rs895520 GG 211 49 0.20 2 Intron   [10, 26, 27, 36,37,38]
   GA 294 76      
   AA 103 37      
  rs2305160 GG 283 75 1.00 2 Exon Thr>Ala [10, 14, 15, 21, 23, 26, 27, 34,35,36,37,38,39,40,41,42,43,44,45]
   GA 264 71      
   AA 59 16      
PER1 rs3027178 TT 281 84 0.29 17 Exon Thr>Thr [10, 17, 28, 46]
   TG 253 64      
   GG 76 14      
PER2 rs934945 CC 386 118 0.07 2 Exon Gly>Glu [10, 17, 24,25,26,27,28, 36, 37, 46]
   CT 206 42      
   TT 17 2      
  rs7602358 TT 358 87 0.49 2 Intron   [10, 23, 27, 36,37,38, 40]
   TG 213 64      
   GG 38 11      
RORA rs339972 TT 312 97 0.15 15 Intron   [10, 27, 36, 37]
   TC 233 53      
   CC 62 12      
  rs10519097 CC 422 110 0.67 15 Intron   [10, 27, 36, 37]
   CT 173 50      
   TT 14 2      
TIMELESS rs774027 AA 157 44 0.63 12 Exon Ile > Val [10, 23, 27, 38]
   AT 301 74      
   TT 148 44      
  rs3809125 CC 250 70 0.87 12 Upstream   
   CT 280 71      
   TT 74 20      
  rs7302060 TT 181 55 0.53 12 Intron   [10, 20,21,22]
   TC 304 74      
   CC 121 33      
  1. Ctrl controls, P-val P value, Chr chromosome, Region Gene region, Residue residue change, Ref in cancer reference in the literature regarding cancer associations