A


miRNA

AUC


Before radiation

After radiation


miR4943p

0.552

0.636

let7b5p

0.722

0.552

miR323a3p

0.562

0.512

miR19b3p

0.603

0.547

miR3425p

0.762

0.527

miR374a5p

0.568

0.625

miR519d

0.658

0.647

 The expression of 22 candidate miRNAs were changed to the ratio form to eliminate normalization issue in plasma. The top five miRNA ratios were statistically calculated their AUC values by ROC analysis form (A) before radiation group and (B) after radiation group
B


miRNA ratio

AUC


Before radiation

130a3p/let7b5p

0.788

130a3p/19b3p

0.763

130a3p/374a5p

0.763

130a3p/175p

0.745

106a5p/130a3p

0.732

After radiation

130a3p/let7b5p

0.752

6285p/let7b5p

0.714

130a3p/148a3p

0.686

148a3p/4943p

0.676

148a3p/6285p

0.671

 The expression of 22 candidate miRNAs were changed to the ratio form to eliminate normalization issue in plasma. The top five miRNA ratios were statistically calculated their AUC values by ROC analysis form (A) before radiation group and (B) after radiation group