Evaluation of the prognostic value of paraoxonase 1 in the recurrence and metastasis of hepatocellular carcinoma and establishment of a liver-specific predictive model of survival

Table 1 Association of PON1 with clinicopathological characteristics of HCC

Clinical factors	PON1 level		Total (n = 369)	95% CI		P-value
Group	High (n = 184)	Low (n = 185)	Total (n = 369)	95% CI		P-value
Gender
F	40	81	121	0.2198819	0.575337	8.10E−06
M	144	104	248	0.2198819	0.575337	8.10E−06
Age (mean, SD)	61.17	57.64		0.7774031	6.287814	0.01212
Tumor pathologic_stage
Stage I–II	145	129	256	1.140819	3.267362	0.009873
Stage III–IV	36	56	89	1.140819	3.267362	0.009873
Tumor size
T1–T2	145	129	274	1.052772	2.921888	0.02976
T3–T4	36	56	92	1.052772	2.921888	0.02976
Tumor metastasis
M0	129	136	265	0.2244094	150.4063	0.623
M1	1	3	4	0.2244094	150.4063	0.623
Tumor nodes
N0	120	130	250	0.2181723	146.4568	0.6237
N1	1	3	4	0.2181723	146.4568	0.6237
Child–Pugh classification
A	115	101	216			0.1671
B	15	6	21
C	1	0	1
Grade
G1	36	19	55			9.62E−05
G2	99	77	176
G3	42	79	121
G4	4	8	12
Race
American indian or alaska tive	1	1	2			0.1536
Asian	68	90	158
Black or african american	10	7	17
White	98	84	182
Tumor status
Tumor free	119	114	233	0.7075	1.8518	0.6426
With tumor	52	57	109	0.7075	1.8518	0.6426
Vascular invasion
Macro	6	9	15			0.00552
Micro	35	57	92
Non-vascular invasion	118	88	206
Hepatic_infalmmation_adj_tissue
Mild	44	55	99			0.02331
Severe	10	8	18
None	73	43	116
AFP (mean, SD)	16352.55	11481.7				0.7408

ISSN: 1479-5876