Therapeutic value of surgical paraaortic staging in locally advanced cervical cancer: a multicenter cohort analysis from the FRANCOGYN study group

Table 3 Multivariate analysis of factors influencing DFS and OS using cox model

Variable	DFS			OS
Variable	OR	CI (95%)	p-value	OR	CI (95%)	p-value
Age at diagnosis	1.0	1.0–1.0	0.69	1.0	1.0–1.0	0.98
BMI ≥ 30	1.1	0.7–1.6	0.68	1.1	0.7–1.8	0.7
FIGO stage ≥ III	2.2	0.9–4.9	0.06	3.8	1.5–9.8	0.006
Tumor size ≥ 4 cm	1.1	0.8–1.6	0.52	0.8	0.5–1.4	0.49
Hydronephrosis on pre-RCC MRI	0.8	0.5–1.4	0.44	0.7	0.4–1.3	0.31
Parametrial invasion on pre-RCC MRI	1.0	0.5–1.7	0.89	0.5	0.3–1.0	0.057
Surgical paraaortic staging	0.64	0.46–0.89	0.008	0.43	0.27–0.68	< 0.001
Intracavitary brachytherapy	0.7	0.5–1.0	0.04	0.6	0.4–0.9	0.02
Completion surgery following CRT	0.7	0.5–1.0	0.03	1.0	0.6–1.6	0.91

Significant factors for both DFS and OS are surgical staging and intracavitary brachytherapy associated with RCC