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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Optimizing bone wound healing using BMP2 with absorbable collagen sponge and Talymed nanofiber scaffold

Fig. 4

Assessment of osteoid tissue within healing defects. a Representative Mason’s Trichrome stained healing defects with ACS (left) and ACS/Talymed (right). BMP2 dose increases from top to bottom. Arrows indicate areas of osteoid tissue. Note greater density and organization of osteoid tissue in the ACS only specimen. 10× magnification. b Quantification of osteoid area indicates greater osseous healing with the ACS only scaffold and with BMP2 treatment. Note that the ACS with medium BMP2 precipitated the most osteoid tissue. n = 3 sections 40 µm apart from at least four individuals per group **p ≤ 0.01, ***p ≤ 0.001

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