Skip to main content

Table 1 Derived glycan traits defined from directly measured glycan peaks

From: N-glycosylation patterns of plasma proteins and immunoglobulin G in chronic obstructive pulmonary disease

Derived plasma glycan trait Description Formula Example of a glycan structure
LB Proportion of mono- and biantennary structures in the total plasma N-glycome GP1 + GP2/2 + GP3 + GP4 + GP5 + GP6 +  GP8 + GP9 + GP10 + GP11 + GP12 + GP13 + GP14 + GP15 + GP16 + GP17 + GP18 + GP20 + GP21 + GP22 + GP23
HB Proportion of tri- and tetraantennary structures in the total plasma N-glycome GP24 + GP25 + GP26 + GP27 + GP28 + GP29 + GP30 + GP31 + GP32 + GP33 + GP34 + GP35 + GP36 + GP37 + GP38 + GP39
G0 Proportion of agalactosylated structures in the total plasma N-glycome GP1 + GP2/2
G1 Proportion of monogalactosylated structures in the total plasma N-glycome GP3 + GP4 + GP5 + GP6 + GP12 + GP13
G2 Proportion of digalactosylated structures in the total plasma N-glycome GP8 + GP9 + GP10 + GP11 + GP14 + GP15 + GP16 + GP17 + GP18 + GP20 + GP21 + GP22 + GP23
G3 Proportion of trigalactosylated structures in the total plasma N-glycome GP24 + GP25 + GP26 + GP27 + GP28 + GP29 + GP30 + GP31 + GP32 + GP35
G4 Proportion of tetragalactosylated structures in the total plasma N-glycome GP33 + GP34 + GP36 + GP37 + GP38 + GP39
S0 Proportion of asialylated structures in the total plasma N-glycome GP1 + GP2/2 + GP3 + GP4 + GP5 + GP6 + GP8 + GP9 + GP10 + GP11
S1 Proportion of monosialylated structures in the total plasma N-glycome GP12 + GP13 + GP14 + GP15 + GP16 + GP17
S2 Proportion of disialylated structures in the total plasma N-glycome GP18 + GP20 + GP21 + GP22 + GP23 + GP24 + GP25 + GP26
S3 Proportion of trisialylated structures in the total plasma N-glycome GP27 + GP28 + GP29 + GP30 + GP31 + GP32 + GP33 + GP34 + GP35
S4 Proportion of tetrasialylated structures in the total plasma N-glycome GP36 + GP37 + GP38 + GP39
Bisecting Proportion of structures containing bisecting GlcNAc in the total plasma N-glycome GP2/2 + GP3 + GP6 + GP9 + GP11 + GP12 + GP15 + GP17 + GP21 + GP23
OligoMan Proportion of oligomannosidic structures in the total plasma N-glycome GP2/2 + GP7 + GP19
CoreF Proportion of structures containing core fucose in the total plasma N-glycome GP1 + GP2/2 + GP4 + GP5 + GP6 + GP10 + GP11 + GP13 + GP16 + GP17 + GP22 + GP23 + GP29 + GP31
AntF Proportion of structures containing antennary fucose in the total plasma N-glycome GP32 + GP35 + GP39
Derived IgG glycan trait Description Formula Example of a glycan structure
G0 Proportion of agalactosylated structures in the total IgG N-glycome IGP1 + IGP2 + IGP3 + IGP4 + IGP5 + IGP6
G1 Proportion of monogalactosylated structures in the total IgG N-glycome IGP7 + IGP8 + IGP9 + IGP10 + IGP11 + IGP16
G2 Proportion of digalactosylated structures in the total IgG N-glycome IGP12 + IGP13 + IGP14 + IGP15 + IGP17 + IGP18 + IGP19 + IGP21 + IGP22 + IGP23 + IGP24
S0 Proportion of asialylated structures in the total IgG N-glycome IGP1 + IGP2 + IGP3 + IGP4 + IGP5 + IGP6 + IGP7 + IGP8 + IGP9 + IGP10 + IGP11 + IGP12 + IGP13 + IGP14 + IGP15
S1 Proportion of monosialylated structures in the total IgG N-glycome IGP16 + IGP17 + IGP18 + IGP19
S2 Proportion of disialylated structures in the total IgG N-glycome IGP21 + IGP22 + IGP23 + IGP24
Bisecting Proportion of structures containing bisecting GlcNAc in the total IgG N-glycome IGP3 + IGP6 + IGP10 + IGP11 + IGP13 + IGP15 + IGP19 + IGP22 + IGP24
OligoMan Proportion of oligomannosidic structures in the total IgG N-glycome IGP5
CoreF Proportion of structures containing core fucose in the total IgG N-glycome IGP1 + IGP4 + IGP6 + IGP8 + IGP9 + IGP10 + IGP11 + IGP14 + IGP15 + IGP16 + IGP18 + IGP19 + IGP23 + IGP24
  1. GlcNAc: N-acetylglucosamine