Fig. 3

Differences in abundance of plasma protein glycan traits between COPD subjects in different GOLD stages and healthy controls. Only the most significant differences are depicted, resulting from case-control meta-analysis, performed on both herein studied cohorts. Differences in N-glycan abundances are shown as box plots. Each box represents the 25th to 75th percentile. Lines inside the boxes represent the median. The upper whisker extends from 75th percentile to the values within 1.5 × IQR (where IQR is the inter-quartile range, or distance between the first and third quartiles). The lower whisker extends from 25th percentile to the values within 1.5 × IQR. Data beyond the end of the whiskers are called “outlying” points and are plotted individually. AntF: antennary fucosylation; G4: tetragalactosylation; GP: glycan peak