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Table 1 Baseline characteristics of the patients by tertiles of serum uromodulin

From: Serum uromodulin and progression of kidney disease in patients with chronic kidney disease

Characteristics Total (N = 2652) Serum uromodulin tertiles (ng/mL)
≤ 52.7 (N = 885) > 52.7–100.8 (N = 881) > 100.8 (N = 886)
Age (years) 48.7 ± 13.8 50.2 ± 13.6 50.0 ± 13.2 45.9 ± 14.1
Male (n%) 1548 (58.4%) 513 (58.0%) 534 (60.6%) 501 (56.6%)
Body mass index (kg/m2) 24.4 ± 3.6 24.2 ± 3.7 24.7 ± 3.7 24.4 ± 3.5
Systolic blood pressure (mmHg) 130.1 ± 19.3 135.7 ± 20.5 130.4 ± 18.4 124.7 ± 17.7
Diastolic blood pressure (mmHg) 81.3 ± 11.7 83.6 ± 12.4 81.6 ± 11.7 78.8 ± 10.4
Smoking status (n%) 907 (38.1%) 325 (42.4%) 300 (38.2%) 282 (34.0%)
Diabetes (n%) 516 (19.6%) 178 (20.3%) 202 (23.1%) 136 (15.4%)
Using anti-hypertensive medications in the past 2 weeks (n%) 1488 (73.2%) 540 (82.3%) 524 (76.7%) 424 (61.1%)
Cardiovascular disease (n%) 293 (12.2%) 121 (15.6%) 114 (14.2%) 58 (7.0%)
Triglyceride (mmol/L) 1.8 (1.3, 2.6) 1.8 (1.3, 2.6) 1.8 (1.3, 2.7) 1.7 (1.2, 2.4)
Total cholesterol (mmol/L) 4.8 (4.0, 5.8) 4.5 (3.7, 5.4) 4.9 (4.1, 5.9) 5.0 (4.1, 6.2)
High-density lipoprotein cholesterol (mmol/L) 1.1 (0.9, 1.3) 1.0 (0.9, 1.2) 1.1 (0.9, 1.3) 1.2 (1.0, 1.4)
Low-density lipoprotein cholesterol (mmol/L) 2.6 (2.1, 3.3) 2.4 (2.0, 3.0) 2.6 (2.1, 3.3) 2.8 (2.2, 3.5)
Fasting blood glucose (mmol/L) 4.9 (4.4, 5.6) 4.9 (4.4, 5.6) 5.0 (4.4, 5.7) 4.9 (4.4, 5.5)
Prealbumin (g/L) 326.5 ± 83.1 348.7 ± 87.6 327.6 ± 79.3 303.2 ± 75.6
High sensitive–reactive protein (mg/L) 1.3 (0.5, 3.0) 1.5 (0.6, 3.6) 1.4 (0.6, 3.1) 1.0 (0.4, 2.5)
Urinary albumin/creatinine ratio (mg/g) 473.7 (134.1, 1046.6) 661.7 (233.9, 1352.8) 439.9 (113.2, 969.9) 374.3 (100.0, 836.6)
Creatinine (μmol/L) 173.8 ± 121.8 247.4 ± 138.6 165.7 ± 114.5 108.4 ± 49.1
Estimated glomerular filtration rate (mL/min/1.73 m2) 49.6 ± 29.4 28.5 ± 15.0 46.3 ± 23.0 74.0 ± 28.0
Estimated glomerular filtration rate group (mL/min/1.73 m2)
 ≥ 90 337 (12.7%) 5 (0.6%) 58 (6.6%) 274 (30.9%)
 60–89 451 (17.0%) 31 (3.5%) 111 (12.6%) 309 (34.9%)
 45–59 419 (15.8%) 73 (8.3%) 211 (24.0%) 135 (15.2%)
 30–44 634 (23.9%) 211 (23.8%) 297 (33.7%) 126 (14.2%)
 15–29 811 (30.6%) 565 (63.8%) 204 (23.2%) 42 (4.7%)
  1. Missing counts: body mass index: 396, systolic blood pressure: 492, diastolic blood pressure: 492, smoking status: 271, diabetes: 16, using anti-hypertensive medications in the past 2 weeks: 619, cardiovascular disease: 240, triglyceride: 64, total cholesterol: 68, high-density lipoprotein cholesterol: 80, low-density lipoprotein cholesterol: 81, fasting blood glucose: 96, prealbumin: 151, high sensitive-reactive protein: 606, urinary albumin/creatinine ratio: 299