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Table 1 Baseline characteristics of the patients by tertiles of serum uromodulin

From: Serum uromodulin and progression of kidney disease in patients with chronic kidney disease

Characteristics

Total (N = 2652)

Serum uromodulin tertiles (ng/mL)

≤ 52.7 (N = 885)

> 52.7–100.8 (N = 881)

> 100.8 (N = 886)

Age (years)

48.7 ± 13.8

50.2 ± 13.6

50.0 ± 13.2

45.9 ± 14.1

Male (n%)

1548 (58.4%)

513 (58.0%)

534 (60.6%)

501 (56.6%)

Body mass index (kg/m2)

24.4 ± 3.6

24.2 ± 3.7

24.7 ± 3.7

24.4 ± 3.5

Systolic blood pressure (mmHg)

130.1 ± 19.3

135.7 ± 20.5

130.4 ± 18.4

124.7 ± 17.7

Diastolic blood pressure (mmHg)

81.3 ± 11.7

83.6 ± 12.4

81.6 ± 11.7

78.8 ± 10.4

Smoking status (n%)

907 (38.1%)

325 (42.4%)

300 (38.2%)

282 (34.0%)

Diabetes (n%)

516 (19.6%)

178 (20.3%)

202 (23.1%)

136 (15.4%)

Using anti-hypertensive medications in the past 2 weeks (n%)

1488 (73.2%)

540 (82.3%)

524 (76.7%)

424 (61.1%)

Cardiovascular disease (n%)

293 (12.2%)

121 (15.6%)

114 (14.2%)

58 (7.0%)

Triglyceride (mmol/L)

1.8 (1.3, 2.6)

1.8 (1.3, 2.6)

1.8 (1.3, 2.7)

1.7 (1.2, 2.4)

Total cholesterol (mmol/L)

4.8 (4.0, 5.8)

4.5 (3.7, 5.4)

4.9 (4.1, 5.9)

5.0 (4.1, 6.2)

High-density lipoprotein cholesterol (mmol/L)

1.1 (0.9, 1.3)

1.0 (0.9, 1.2)

1.1 (0.9, 1.3)

1.2 (1.0, 1.4)

Low-density lipoprotein cholesterol (mmol/L)

2.6 (2.1, 3.3)

2.4 (2.0, 3.0)

2.6 (2.1, 3.3)

2.8 (2.2, 3.5)

Fasting blood glucose (mmol/L)

4.9 (4.4, 5.6)

4.9 (4.4, 5.6)

5.0 (4.4, 5.7)

4.9 (4.4, 5.5)

Prealbumin (g/L)

326.5 ± 83.1

348.7 ± 87.6

327.6 ± 79.3

303.2 ± 75.6

High sensitive–reactive protein (mg/L)

1.3 (0.5, 3.0)

1.5 (0.6, 3.6)

1.4 (0.6, 3.1)

1.0 (0.4, 2.5)

Urinary albumin/creatinine ratio (mg/g)

473.7 (134.1, 1046.6)

661.7 (233.9, 1352.8)

439.9 (113.2, 969.9)

374.3 (100.0, 836.6)

Creatinine (μmol/L)

173.8 ± 121.8

247.4 ± 138.6

165.7 ± 114.5

108.4 ± 49.1

Estimated glomerular filtration rate (mL/min/1.73 m2)

49.6 ± 29.4

28.5 ± 15.0

46.3 ± 23.0

74.0 ± 28.0

Estimated glomerular filtration rate group (mL/min/1.73 m2)

 ≥ 90

337 (12.7%)

5 (0.6%)

58 (6.6%)

274 (30.9%)

 60–89

451 (17.0%)

31 (3.5%)

111 (12.6%)

309 (34.9%)

 45–59

419 (15.8%)

73 (8.3%)

211 (24.0%)

135 (15.2%)

 30–44

634 (23.9%)

211 (23.8%)

297 (33.7%)

126 (14.2%)

 15–29

811 (30.6%)

565 (63.8%)

204 (23.2%)

42 (4.7%)

  1. Missing counts: body mass index: 396, systolic blood pressure: 492, diastolic blood pressure: 492, smoking status: 271, diabetes: 16, using anti-hypertensive medications in the past 2 weeks: 619, cardiovascular disease: 240, triglyceride: 64, total cholesterol: 68, high-density lipoprotein cholesterol: 80, low-density lipoprotein cholesterol: 81, fasting blood glucose: 96, prealbumin: 151, high sensitive-reactive protein: 606, urinary albumin/creatinine ratio: 299