Table 3 Correlations between clinicopathological features and axillary lymph node metastasis
Parameters | Axillary lymph node | p value | |
|---|---|---|---|
Negative (n = 12) | Positive (n = 4) | ||
Age | |||
 ≤ 47 | 6 (50.0%) | 2 (50.0%) |  |
 > 47 | 6 (50.0%) | 2 (50.0%) | 1.000 |
Tumor size | |||
 ≤ 25 | 7 (58.3%) | 1 (25.0%) |  |
 > 25 | 5 (41.7%) | 3 (75.0%) | 0.278 |
Estrogen receptor | |||
 Negative | 6 (50.0%) | 1 (25.0%) |  |
 Positive | 6 (50.0%) | 3 (75.0%) | 0.417 |
Progesterone receptor | |||
 Negative | 8 (66.7%) | 2 (50.0%) |  |
 Positive | 4 (33.3%) | 2 (50.0%) | 0.582 |
HER2 | |||
 Negative | 4 (33.3%) | 4 (100.0%) |  |
 Positive | 8 (66.7%) | 0 (0.0%) | 0.019 |
Ki67 | |||
 Negative | 3 (25.0%) | 1 (25.0%) |  |
 Positive | 9 (75.0%) | 3 (75.0%) | 1.000 |
Intrinsic subtype HRBC | |||
 Non-HRBC | 6 (50.0%) | 1 (25.0%) |  |
 HRBC | 6 (50.0%) | 3 (75.0%) | 0.417 |
Intrinsic subtype HER2BC | |||
 Non-HER2BC | 8 (66.7%) | 4 (100.0%) |  |
 HER2BC | 4 (33.3%) | 0 (0.0%) | 0.207 |
Intrinsic subtype TNBC | |||
 Non-TNBC | 10 (83.3%) | 3 (75.0%) |  |
 TNBC | 2 (16.7%) | 1 (25.0%) | 0.734 |
TILs | |||
 Low | 1 (8.3%) | 3 (75.0%) |  |
 High | 11 (91.7%) | 1 (25.0%) | 0.005 |
Number of sentinel lymph nodes with metastasis | |||
 1, 2 | 11 (91.7%) | 2 (50.0%) |  |
 3 | 1 (8.3%) | 2 (50.0%) | 0.071 |
Size of sentinel lymph node itself (mm) | |||
 ≤ 12.5 | 6 (50.0%) | 2 (50.0%) |  |
 > 12.5 | 6 (50.0%) | 2 (50.0%) | 1.000 |
Size of metastatic lesion | |||
 ≤ 3400 | 6 (50.0%) | 2 (50.0%) |  |
 > 3400 | 6 (50.0%) | 2 (50.0%) | 1.000 |
Clinical response | |||
 cPR | 10 (83.3%) | 4 (100.0%) |  |
 cCR | 2 (16.7%) | 0 (0.0%) | 0.417 |
Pathological complete response | |||
 Non-pCR | 8 (66.7%) | 3 (75.0%) |  |
 pCR | 4 (33.3%) | 1 (25.0%) | 0.774 |