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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Platycodin D inhibits platelet function and thrombus formation through inducing internalization of platelet glycoprotein receptors

Fig. 7

Expression of platelet glycoprotein receptors αIIbβ3, GPIbα and GPVI. After PD treatment, the expression of platelet αIIbβ3, GPIbα and GPVI was measured by flow cytometry (mean ± SD, n = 3) (ac) and western blot (d). Prior to PD treatment, washed platelets were treated with cytochalasin D (CD) (20 μM), BAPTA-AM (BAPTA) (20 μM), wortmannin (WM) (10 μM) or GM6001 (100 μM) followed by measuring the surface expression of platelet αIIbβ3, GPIbα and GPVI by flow cytometry (mean ± SD, n = 3) (eg). Compared with 0, *P < 0.05; ***P < 0.001

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