Table 2 Clinical characteristics of patients across tertiles of serum Angpt-2
Variables | Serum Angpt-2 in tertiles | p for trend | ||
|---|---|---|---|---|
Lower (n = 108) | Middle (n = 108) | Upper (n = 108) | ||
Age (year) | 55.2 ± 14.5 | 57.8 ± 13.5 | 59.3 ± 14.1 | 0.1 |
Male gender (n [%]) | 56 (52%) | 56 (52%) | 54 (50%) | 0.9 |
Dialysis duration (mo) | 25.6 (3.2–55.1) | 34.9 (12.6–60.7) | 34.6 (15.1–55.8) | 0.3 |
Diabetes mellitus (n [%]) | 22 (20.4%) | 28 (25.9%) | 34 (31.5%) | 0.2 |
Body mass index (kg/m2) | 22.1 ± 3.8 | 23.2 ± 3.7 | 24.3 ± 4.1 | < 0.001 |
Background AVD (n [%]) | 26 (24.1%) | 34 (31.5%) | 39 (36.1%) | 0.2 |
Background VC (n [%]) | 17 (15.7%) | 22 (20.4%) | 28 (25.9%) | 0.2 |
Hemoglobin (g/L) | 107.7 ± 15.7 | 107.7 ± 16.8 | 106.7 ± 18.6 | 0.9 |
Serum albumin (g/L) | 37.0 ± 4.6 | 37.0 ± 4.5 | 37.1 ± 4.8 | 0.9 |
n PCR | 0.93 ± 0.19 | 0.87 ± 0.19 | 0.83 ± 0.15 | < 0.001 |
Ca × P (mg2/dL2) | 54 ± 17 | 58 ± 17 | 62 ± 22 | 0.009 |
iPTH (pg/L) | 269 (124.9–568.0) | 266.0 (133.3–563.5) | 376 (149.8–616.3) | 0.3 |
hs-CRP (mg/L) | 1.37 (0.65–3.73) | 2.63 (0.89–5.72) | 3.7 (1.45–8.38) | < 0.001 |
BNP (pg/mL) | 66.5 (23.0–158.8) | 89 (50.5–202.8) | 97.5 (44.0–198.8) | 0.006 |
Total cholesterol (mmol/L) | 4.77 (4.05–5.40) | 5.05 (4.25–5.69) | 4.64 (3.97–5.50) | 0.08 |
LDL cholesterol (mmol/L) | 2.68 (2.14–3.26) | 2.85 (2.24–3.40) | 2.56 (1.83–3.07) | 0.03 |
HDL cholesterol (mmol/L) | 1.17 (0.92–1.58) | 1.16 (0.93–1.50) | 1.10 (0.86–1.31) | 0.07 |
Triglyceride (mmol/L) | 1.50 (1.13–2.24) | 1.67 (1.17–2.46) | 1.85 (1.22–3.03) | 0.08 |
LV mass index (g/m2) | 114.9 (82.2–159.4) | 128.3 (91.8–177.5) | 136.0 (92.9–189.8) | 0.2 |
LV ejection fraction (%) | 67 (64–71) | 65.5 (60–69.8) | 64 (58–68.5) | 0.005 |
Total weekly urine clearance | 2.05 ± 0.41 | 1.91 ± 0.36 | 1.86 ± 0.30 | 0.001 |
Total weekly creatinine clearance (L/wk/1.73 m2) | 67.68 ± 21.42 | 61.47 ± 17.40 | 56.88 ± 13.61 | < 0.001 |
Residual renal function (mL/min) | 1.96 (0.53–4.18) | 0.77 (0–2.52) | 0.21 (0–1.88) | < 0.001 |