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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Matrine attenuates endoplasmic reticulum stress and mitochondrion dysfunction in nonalcoholic fatty liver disease by regulating SERCA pathway

Fig. 7

Mat modulates calcium homeostasis via the SERCA pathway. a computation docking of SERCA1a or SERCA2 with Mat (depicted in colored yellow). CPA (depicted in colored grey) and Tg (depicted in colored purple). In the activity test of SERCA (b and c), the L02 cells were treated with PA (500 μM), Mat (200, 400, 800 μM) or the combination of PA (500 μM) and Mat (200, 400, 800 μM) for 12 h. b the SERCA activity of the combination of PA and Mat. c the SERCA activity of Mat incubated alone. *P < 0.05 and **P < 0.01

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