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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Matrine attenuates endoplasmic reticulum stress and mitochondrion dysfunction in nonalcoholic fatty liver disease by regulating SERCA pathway

Fig. 4

Effect of Mat on ER stress in PA-induced L02 cells. The L02 cells were treated with PA (500 μM) or the combination of PA (500 μM) and Mat (200, 400, 800 μM) for 12 h. a Western blot analysis for expression of ER stress signal proteins in L02 cells:p-PERK, p-IRE1, PERK, IRE1, ATF6, GRP78 and CHOP. PA + Mat groups (L, H) represent PA (500 μM) combined with Mat 200 μM and 800 μM, respectively. b ER histochemistry (×400) of ATF6, GRP78 and CHOP. *P < 0.05 and **P < 0.01

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