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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Matrine attenuates endoplasmic reticulum stress and mitochondrion dysfunction in nonalcoholic fatty liver disease by regulating SERCA pathway

Fig. 2

Mat alleviates ER stress and inflammatory responses in MCD mice (n = 10 animals per condition). a HE staining (×200) and Oil red O staining (×200) of livers in MCD mice. b Serum ALT and AST levels (markers of hepatic injury). c Serum TNF-α, IL-6 and IL-10 (inflammatory factors) levels. d Western blot analysis for expression of ER stress signal proteins in liver: p-PERK, p-IRE1, PERK, IRE1, ATF6, GRP78 and CHOP. *P < 0.05 and **P < 0.01

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