Fig. 1
From: GAP43, a novel metastasis promoter in non-small cell lung cancer
Expression of GAP43 in NSCLC. a, b Brain metastasis-free and overall survival curves of 70 patients with NSCLC based on the expression levels of GAP43. The P values were calculated using a log-rank test. c, d Progression-free and overall survival curves according to the expression levels of GAP43 in patients with lung cancer generated by a public database and web application called KM plotter (http://kmplot.com/analysis/index.php?p=service&cancer=lung). e Representative images of immunohistochemistry staining for GAP43 expression in primary NSCLC tissues and corresponding brain metastasis tissues; magnification, ×400. A total of 3/5 brain metastasis tissues showed an elevated level of GAP43 expression compared with paired NSCLC tissues. f Expression levels of GAP43 in NSCLC cells evaluated by western blotting