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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Simvastatin attenuates tibial bone loss in rats with type 1 diabetes and periodontitis

Fig. 1

Experimental scheme and the effects of SIM on body weight and fasting glucose level. Rats were divided into three groups: C, DP, and DPS. a Experimental scheme: 7 days after induction of diabetes by STZ (50 mg/kg) injection, periodontitis was induced by ligatures of the mandibular first molars using dental floss (day 0). After placement of the ligatures, the DPS group was orally administered SIM (30 mg/kg) daily for a duration of 3, 10, or 20 days. b Body weight and c fasting glucose level in each group. Data are presented as the mean ± SE. *P < 0.05 compared with the C group. **P < 0.05

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