Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 4 Anthropometric, body composition and REE analysis for FTO rs9939609 A carriers vs TT genotype in MeD and CTR groups

From: Influence of FTO rs9939609 and Mediterranean diet on body composition and weight loss: a randomized clinical trial

  TT genotype A carriers P main effect of FTO rs9939609 P main effect of diet P main effect gene-diet interaction
MeD CTR MeD CTR
(n = 40) (n = 17) (n = 99) (n = 32)
Weight (kg)      0.85 0.43 0.87
 Baseline 79.63 (21.56) 73.33 (17.26) 83.29 (22.73) 78.73 (15.87)    
 Change − 3.41 (6.47) − 1.27 (3.89) − 2.25 (11.79) − 0.62 (1.26)    
BMI      0.92 0.33 0.81
 Baseline 29.03 (7.39) 25.74 (3.64) 30.4 (7.35) 28.50 (6.03)    
 Change − 1.28 (2.34) − 0.30 (0.82) − 0.85 (4.27) − 0.18 (0.80)    
Neck circumference (cm)      0.50 0.78 0.37
 Baseline 40.54 (3.39) 36.75 (3.28) 41.03 (4.19) 36.88 (3.76)    
 Change − 0.60 (0.42) − 0.40 (0.96) − 1.09 (2.13) − 0.07 (1.12)    
Waist circumference (cm)      0.80 0.87 0.86
 Baseline 88.17 (19.18) 86.81 (11.66) 94.14 (17.25) 87.7 (12.72)    
 Change − 1.10 (3.03) − 0.78 (1.82) − 1.91 (7.55) − 1.10 (2.34)    
Abdomen circumference (cm)      0.87 0.97 0.28
 Baseline 104.92 (18) 93.74 (9.66) 107.49 (15.9) 99.48 (14.6)    
 Change − 0.80 (1.48) − 1.04 (3.46) − 3.73 (6.51) − 1.13 (2.89)    
Hip circumference (cm)      0.93 0.70 0.76
 Baseline 103.8 (11.16) 102.72 (7.68) 107.68 (13.01) 107.67 (12.13)    
 Change − 1.90 (4.04) − 1.38 (3.55) − 2.51 (3.93) − 1.44 (3.29)    
WHR      0.80 0.89 0.89
 Baseline 0.84 (0.12) 0.84 (0.08) 0.87 (0.12) 0.82 (0.08)    
 Change 0.00 (0.02) 0.00 (0.03) 0.00 (0.07) 0.00 (0.03)    
R      0.10 0.98 0.87
 Baseline 533.35 (88.18) 545.31 (80.2) 484.66 (107.09) 507.77 (78.38)    
 Change − 3.00 (22.26) 0.24 (33.1) 20.11 (59.77) 25.91 (42.27)    
Xc      0.38 0.32 0.38
 Baseline 55.8 (11.45) 58.81 (8.83) 54.98 (15.84) 54.84 (10.33)    
 Change 0.00 (4.76) − 4.53 (6.69) − 2.2 (10.33) − 2.13 (8.13)    
PA      0.73 0.45 0.58
 Baseline 6.23 (1.06) 6.24 (1.22) 6.62 (1.54) 6.22 (1.07)    
 Change 0.10 (0.34) − 0.40 (0.79) − 0.47 (1.57) − 0.53 (0.94)    
BCM (kg)      0.17 0.91 0.94
 Baseline 27.29 (6.39) 28.95 (8.13) 31.99 (9.68) 29.66 (6.28)    
 Change − 0.33 (0.98) − 0.54 (3.51) − 2.62 (7.63) − 2.75 (4.26)    
Na/K      0.64 0.66 0.53
 Baseline 0.97 (0.12) 0.98 (0.13) 0.91 (0.18) 0.96 (0.13)    
 Change 0.03 (0.1) 0.06 (0.1) 0.06 (0.17) − 0.12 (0.63)    
TBW (L)      0.02* 0.48 0.47
 Baseline 38.36 (8.55) 38.54 (8.94) 41.76 (10.99) 39.81 (6.57)    
 Change − 0.83 (1.63) 0.70 (3.04) − 1.88 (4.35) − 1.75 (3.28)    
ECW (L)      0.81 0.43 0.56
 Baseline 17.23 (4.06) 17.22 (3.9) 18.01 (5.27) 17.89 (3.04)    
 Change − 0.25 (1.5) 2.00 (3.26) 2.16 (6.74) 2.42 (4.07)    
ICW (L)      0.65 0.92 0.81
 Baseline 21.12 (5.16) 17.22 (3.9) 23.75 (6.97) 20.59 (4.05)    
 Change − 0.25 (0.74) − 0.54 (1.8) − 1.89 (4.85) − 0.95 (1.79)    
BCMI      0.70 0.91 0.52
 Baseline 12.77 (7.02) 10.11 (1.96) 13.9 (8.08) 10.56 (1.94)    
 Change − 0.10 (0.34) − 0.34 (1) − 2.40 (6.81) − 0.85 (1.23)    
Android Bfat (%)      0.60 0.09 0.93
 Baseline 44.92 (12.45) 37.34 (8.78) 44.88 (12.77) 39.79 (12.61)    
 Change − 4.52 (6.01) − 1.00 (2.16) − 2.96 (4.64) 0.15 (1.7)    
Gynoid Bfat (%)      0.70 0.04* 0.32
 Baseline 43.51 (10.63) 36 (7.85) 41.8 ( 77(11.76) 39.07 (9.37)    
 Change − 2.94 (5.14) 0.03 (1.26) − 1.67 (3.51) − 0.42 (1.74)    
TBFat (%)      0.79 0.08 0.94
 Baseline 37.92 (9.45) 33.16 (6.05) 38.08 (10.34) 36.14 (9.52)    
 Change − 2.74 (3.45) − 0.19 (1.14) − 2.01 (3.65) 0.31 (0.9)    
Android Bfat (kg)      0.89 0.27 0.91
 Baseline 3.02 (1.96) 2.32 (1.08) 3.3 (2.17) 2.78 (1.39)    
 Change − 0.47 (0.53) − 0.04 (0.27) − 0.45 (1.18) − 0.12 (0.63)    
Gynoid Bfat (kg)      0.49 0.84 0.40
 Baseline 5.57 (2.19) 4.37 (1.45) 5.49 (2.58) 5.78 (1.79)    
 Change − 0.62 (0.85) − 0.46 (1.25) − 0.36 (2.82) − 0.94 (2.25)    
TBFat (Kg)      0.06 0.00* 0.04*
 Baseline 31.34 (14.5) 21.32 (8.66) 32.85 (15.56) 23.24 (12.11)    
 Change − 3.59 (4.78) 1.93 (5.54) − 3.97 (6.97) 6.11 (9.60)    
Android BLean (kg)      0.97 0.32 0.12
 Baseline 3.32 (1.01) 3.31 (0.86) 3.2 (0.91) 3.31 (0.62)    
 Change − 0.22 (0.87) − 0.08 (0.15) 0.11 (0.6) − 0.08 (0.27)    
Gynoid BLean (kg)      0.49 0.92 0.91
 Baseline 6.77(1.86) 7.24(2.16) 6.79(1.9) 7.08(1.26)    
 Change − 0.20(1.54) − 0.18(0.31) − 0.56(5.66) 0.01(0.33)    
TBLean (kg)      0.92 0.63 0.87
 Baseline 47.67(11.77) 46.47(11.84) 47.86(11.37) 47.28(8.87)    
 Change − 1.23(6.82) − 0.53(1.05) − 0.56(5.66) − 0.61(2.08)    
REE      0.77 0.27 0.49
 Baseline 1639.92 (409.68) 1664.96 (217.89) 1628.13 (347.37) 1583.46 (313.51)    
 Change − 48.13 (327.01) − 31.44 (140.89) − 44.01 (220.32) − 7.49 (34.75)    
  1. Relationship between FTO rs9939609 A carriers and TT genotype in body composition and metabolism, according to MeD and CTR groups. Statistical significance (*) were given to results with p < 0.05 through GLM analysis. BMI body mass index, WHR waist hip ratio, R resistance, Xc reactance, PA phase angle, HYDR hydration, NA/K sodium–potassium exchange, TBW total body water, ECW extracellular water, ICW intracellular water, BFat body fat, TBFat total body fat, BLean body lean, TBLean total body lean, REE resting energy expenditure