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Table 5 Predictive parameters of long-term outcomes (death and hospitalizations for MACE) (Cox model)

From: Galectin-3 predicts response and outcomes after cardiac resynchronization therapy

 

Univariate

HR [CI 95%]

p*

Multivariate

HR [CI 95%]

p*

Age ≥ 65 year-old

1.89 [0.29–7.37]

0.45

  

CAD

3.62 [1.07–16.41]

0.04

2.64 [0.72–12.54]

0.15

Female sex

0.86 [0.19–2.89]

0.82

  

Minnesota ≥ 46

0.71 [0.22–2.72]

0.59

  

Gal-3 ≥ 22 (ng/mL)

4.33 [1.34–14.01]

0.02

3.31 [1.00–11.34]

0.05

LVEF ≥ 25%

0.54 [0.17–1.85]

0.31

  

LVESV (mL/m2)

5.54 [0.53–43.11]

0.14

  

Presence of LGE

2.31 [0.73–8.67]

0.16

  

LGE ≥ 14%

2.20 [0.70–7.45]

0.17

  

QRS < 150 ms

3.20 [0.69–11.31]

0.12

  

Selvester ≥ 24%

1.84 [0.49–5.89]

0.34

  

Creatinine clearance (mL/min/1.73 m2)

0.98 [0.95–1.02]

0.12

  

Diabetes

1.24 [0.39–4.68]

0.71

  
  1. Significant p values are in italics
  2. *A p value ≤ 0.05 was considered significant