Table 1 Univariate and multivariate analysis of prognostic factors associated with overall survival
Characteristics | Patients | Overall survival | |||
|---|---|---|---|---|---|
Univariate analysis p value | Multivariate analysis p value | Multivariate HR | 95% confidence interval (CI) | ||
Total | 90 | ||||
Gender | |||||
Male/female | 56/34 | 0.782 | NA | ||
Age (years) | |||||
< 70/≥ 70 | 64/26 | 0.261 | NA | ||
Primary site | |||||
Head/body or tail | 52/38 | 0.397 | NA | ||
Differentiation | |||||
I/II/III | 1/28/61 | 0.303 | NA | ||
T classification | |||||
≤ 4 cm/> 4 cm | 66/24 | 0.039 | 0.047 | 1.737 | 1.006–2.998 |
N classification | |||||
N0/N1–2 | 53/37 | 0.045 | 0.037 | 1.741 | 1.035–2.927 |
Fibrinogen | |||||
≤ 400/> 400 mg/dL | 75/15 | 0.319 | NA | ||
CA19-9 | |||||
< 37/≥ 37 U/L | 22/68 | 0.207 | NA | ||
CEA | |||||
< 5/≥ 5 ng/mL | 68/22 | 0.619 | NA | ||
TBIL | |||||
≤ 20.4/> 20.4 μmol/L | 56/34 | 0.237 | NA | ||
Albumin | |||||
< 35/≥ 35 g/L | 16/74 | 0.805 | NA | ||
ALT | |||||
≤ 35/> 35 U/L | 50/40 | 0.441 | NA | ||
AST | |||||
≤ 40/> 40 U/L | 54/36 | 0.672 | NA | ||
GGT | |||||
≤ 60/> 60 U/L | 45/45 | 0.766 | NA | ||
ALP | |||||
≤ 125/> 125 U/L | 54/36 | 0.588 | NA | ||
LDH | |||||
≤ 245/> 245 U/L | 76/14 | 0.336 | NA | ||
Glucose | |||||
≤ 5.6/> 5.6 mmol/L | 38/52 | 0.090 | NA | ||
TGF-β | |||||
Low/high | 50/40 | < 0.001 | 0.001 | 2.453 | 1.410–4.266 |
IIR | |||||
Low/high | 30/60 | 0.006 | 0.032 | 2.004 | 1.063–3.779 |