|
Characteristics
|
Patients
|
Overall survival
|
|---|
|
Univariate analysis p value
|
Multivariate analysis p value
|
Multivariate HR
|
95% confidence interval (CI)
|
|---|
|
Total
|
90
| | | | |
|
Gender
|
|
Male/female
|
56/34
|
0.782
|
NA
| | |
|
Age (years)
|
|
< 70/≥ 70
|
64/26
|
0.261
|
NA
| | |
|
Primary site
|
|
Head/body or tail
|
52/38
|
0.397
|
NA
| | |
|
Differentiation
|
|
I/II/III
|
1/28/61
|
0.303
|
NA
| | |
|
T classification
|
|
≤ 4 cm/> 4 cm
|
66/24
|
0.039
|
0.047
|
1.737
|
1.006–2.998
|
|
N classification
|
|
N0/N1–2
|
53/37
|
0.045
|
0.037
|
1.741
|
1.035–2.927
|
|
Fibrinogen
|
|
≤ 400/> 400 mg/dL
|
75/15
|
0.319
|
NA
| | |
|
CA19-9
|
|
< 37/≥ 37 U/L
|
22/68
|
0.207
|
NA
| | |
|
CEA
|
|
< 5/≥ 5 ng/mL
|
68/22
|
0.619
|
NA
| | |
|
TBIL
|
|
≤ 20.4/> 20.4 μmol/L
|
56/34
|
0.237
|
NA
| | |
|
Albumin
|
|
< 35/≥ 35 g/L
|
16/74
|
0.805
|
NA
| | |
|
ALT
|
|
≤ 35/> 35 U/L
|
50/40
|
0.441
|
NA
| | |
|
AST
|
|
≤ 40/> 40 U/L
|
54/36
|
0.672
|
NA
| | |
|
GGT
|
|
≤ 60/> 60 U/L
|
45/45
|
0.766
|
NA
| | |
|
ALP
|
|
≤ 125/> 125 U/L
|
54/36
|
0.588
|
NA
| | |
|
LDH
|
|
≤ 245/> 245 U/L
|
76/14
|
0.336
|
NA
| | |
|
Glucose
|
|
≤ 5.6/> 5.6 mmol/L
|
38/52
|
0.090
|
NA
| | |
|
TGF-β
|
|
Low/high
|
50/40
|
< 0.001
|
0.001
|
2.453
|
1.410–4.266
|
|
IIR
|
|
Low/high
|
30/60
|
0.006
|
0.032
|
2.004
|
1.063–3.779
|
- Italic values indicate significance of p value (p<0.05)
