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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: CD25 and TGF-β blockade based on predictive integrated immune ratio inhibits tumor growth in pancreatic cancer

Fig. 2

Combination therapy of anti-CD25 and anti-TGF-β depletes Tregs in PDAC murine models. a Flow cytometry gating schema and density plots for CD3+CD4+FoxP3+ Tregs. b FoxP3 expression in tumor tissues under different therapies. IHC data showing c the amounts of FoxP3+ Tregs. Flow cytometry data showing the percentage of Tregs among CD4+ T cells in d spleen and e blood, and f the percentage of Tregs among CD3+ T cells in tumor. *< 0.05, **< 0.001, ****< 0.0001

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Journal of Translational Medicine

ISSN: 1479-5876

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