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Table 3 Perinatal outcomes among groups with different glucose tolerance and insulin secreting status

From: Heterogeneity of insulin resistance and beta cell dysfunction in gestational diabetes mellitus: a prospective cohort study of perinatal outcomes

 

GDM-resistance

P value

GDM-dysfunction

P value

GDM-mix

P value

All GDM

P value

NGT

Gestational age (week)

39.7 (1.8)

39.4 (1.2)

39.3 (2.0)

39.4 (1.6)

0.964

39.5 (1.6)

Infant birth weight (g)

3260.0 (547.5)

3380.00 (575.0)

3380.0 (720.0)

3365.0 (527.5)

0.546

3340.0 (520.0)

Infant birth weight (z score)

0.20 (1.1)

0.36 (1.4)

0.41 (1.5)

0.31 (1.3)

0.186

0.14 (1.2)

BPD (cm)

93 (5.3)

93 (4.3)

93 (7.0)

93 (6.0)

0.149

94 (5.0)

FL (cm)

68 (3.5)

69 (4.3)

69 (4.0)

69 (4.0)

0.836

69 (4.0)

AFI (mm)

125 (49.8)

115 (32.0)

116 (41.0)

118 (43.75)

0.92

119 (38.5)

Apgar score

10 (0)

10 (0)

10 (0)

10 (0)

0.364

10 (0)

Infant male gender [n, (%)]

17 (48.6)

20 (46.5)

40 (50.6)

104 (50.5)

0.456

135 (54.0)

LGA [n, (%)]

2 (5.7)

0.4

6 (14.0)

0.808

20 (25.3)

0.008

34 (16.5)

0.263

32 (12.8)

Cesarean delivery [n, (%)]

17 (48.6)

19 (44.2)

40 (50.6)

95 (46.1)

0.029

90 (36.0)

Neonate hypoglycemia [n, (%)]

4 (11.4)

4 (9.3)

11 (13.9)

21 (10.2)

0.510

21 (8.4)

Any adverse outcome [n, (%)]

19 (54.3)

0.313

22 (51.2)

0.469

50 (63.3)

0.005

114 (55.3)

0.031

113 (45.2)

  1. Data are median (IQR) for continuous variables and n (%) for categorical variables
  2. Differences between GDM subgroups and women with NGT were evaluated with the Kruskal–Wallis test for continuous variables and χ2 or Fisher exact test for categorical variables
  3. When the P value was significant (< 0.05), Dunn’s multiple comparisons test or χ2 or Fisher exact test was performed to evaluate the difference between each GDM subtype and NGT group. P values for pairwise comparisons were adjusted by Bonferroni correction