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Table 1 Baseline characteristics of pregnant women in different GDM subgroups

From: Heterogeneity of insulin resistance and beta cell dysfunction in gestational diabetes mellitus: a prospective cohort study of perinatal outcomes

 

GDM-resistance

P value

GDM-dysfunction

P value

GDM-mix

P value

GDM-normal

P value

All GDM

P value

NGT

Participants (n)

35 (17.0% of GDM)

 

43 (20.9% of GDM)

 

79 (38.3% of GDM)

 

49 (23.8% of GDM)

 

206

 

250

Age (years)

31.0 (7.5)

> 0.999

31.0 (6.0)

0.021

32.0 (6.0)

< 0.001

31.0 (4.0)

0.824

32.0 (5.0)

< 0.001

29.0 (5.0)

Prepregnancy BMI (kg/m2)

21.5 (3.2)

0.231

21.6 (3.2)

0.405

23.2 (4.0)

< 0.001

20.7 (3.3)

> 0.999

22.0 (3.7)

< 0.001

20.8 (3.7)

Maternal BMI (kg/m2)

23.1 (4.0)

0.071

22.2 (2.9)

0.45

24.5 (4.3)

< 0.001

21.3 (3.3)

> 0.999

23.2 (3.7)

< 0.001

21.8 (3.4)

Gestational age at weight measuring (weeks)

13.3 (3.5)

13.7 (3.3)

13.9 (2.9)

13.9 (2.4)

13.7 (2.8)

0.073

14.0 (3.6)

Maternal BMI change (kg/m2)

0.8 (0.9)

1.1 (1.1)

0.8 (1.3)

0.8 (0.8)

0.8 (1.0)

0.969

0.8 (1.1)

ALT (U/L)

13 (7.5)

14.5 (13.0)

13 (10.0)

12 (8.5)

13 (10.8)

0.753

13 (11.0)

History of hypertension (n)

0

0

4 (5.1)

2 (4.1)

6 (2.9)

0.007

0

Smoking before or during pregnancy (n)

0

0

0

0

0

0

Nulliparous (n)

25 (71.4)

27 (62.8)

53 (67.1)

32 (65.3)

137 (66.5)

0.173

181 (72.4)

  1. Data are median (IQR) for continuous variables and n (%) for categorical variables
  2. Differences between GDM subgroups and women with NGT were evaluated with the Kruskal–Wallis test for continuous variables and χ2 or Fisher exact test for categorical variables
  3. When the P value was significant (< 0.05), Dunn’s multiple comparisons test or χ2 or Fisher exact test was performed to evaluate the difference between each GDM subtype and NGT group. P values for pairwise comparisons were adjusted by Bonferroni correction