Fig. 3

Baseline CTCs and changes in CTCs during treatments according to treatment effects. a Bar charts show details of baseline CTCs according to treatment responses in 18 patients. Total CTCs, mCTCs and eCTCs are indicated in purple, yellow and green, respectively. b Line graphs indicate change in CTCs during eribulin administration according to treatment responses in 15 patients, all of whom received a second CTC test. c Proportions of mCTC and eCTC in individual patients during eribulin administration, according to changes in total CTCs, are shown. As indicated in the grey square, the upper bar shows baseline status, the lower bar that during treatment. Yellow and green bars represent the rates of mCTC and eCTC, respectively