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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Unique true predicted neoantigens (TPNAs) correlates with anti-tumor immune control in HCC patients

Fig. 4

Evaluation of pre-existing immunity to TPNAs in a long-term survivor. a C57BL/6 mice were immunized with the indicated peptides or with PBS. Interferon-γ (IFN-γ) secreting T cells were evaluated in splenocytes from sacrificed animals after in vitro O/N re-stimulation with individual peptides. b PBMCs isolated from patient HLA-008 were stimulated ex vivo with the indicated peptides for 10 days. Interferon-γ (IFN-γ) secreting T cells were evaluated after in vitro O/N restimulation with individual peptides

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