Fig. 4
From: Unique true predicted neoantigens (TPNAs) correlates with anti-tumor immune control in HCC patients
Evaluation of pre-existing immunity to TPNAs in a long-term survivor. a C57BL/6 mice were immunized with the indicated peptides or with PBS. Interferon-γ (IFN-γ) secreting T cells were evaluated in splenocytes from sacrificed animals after in vitro O/N re-stimulation with individual peptides. b PBMCs isolated from patient HLA-008 were stimulated ex vivo with the indicated peptides for 10 days. Interferon-γ (IFN-γ) secreting T cells were evaluated after in vitro O/N restimulation with individual peptides