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Table 1 Clinical characteristics of sJIA patients and healthy controls

From: Plasma interleukin-37 is increased and inhibits the production of inflammatory cytokines in peripheral blood mononuclear cells in systemic juvenile idiopathic arthritis patients

Characteristics Active sJIA (n = 23) Inactiv sJIA (n = 23) sJIA (n = 46) HCs (n = 30)
Age (years) 7.3 ± 3.1 7.4 ± 3.3 7.4 ± 3.2 6.6 ± 2.8
Sex, no. F/M 13/10 7/16 20/26 12/18
Disease duration (years) 2.2 ± 0.88 2.0 ± 0.83 2.1 ± 0.86 N/A
JADAS-27 26.09 ± 7.48 13.94 ± 6.82 20.02 ± 9.37 N/A
ESR, mm/h 48.69 ± 5.64 35.77 ± 6.89 41.53 ± 9.69 N/A
CRP, mg/L 25.87 ± 6.17 21.47 ± 3.36 23.7 ± 4.43 N/A
PLT, 109/L 361.39 ± 91.94 350.22 ± 90.98 357.98 ± 90.37 N/A
ALT, U/L 20.07 ± 19.16 24.73 ± 20.72 22.41 ± 19.87 N/A
AST, U/L 33.32 ± 20.00 36.20 ± 18.97 34.76 ± 19.53 N/A
ANA positivity (%) 3 (13.04) 0 (0) 3 (6.52) N/A
RF positivity (%) 0 (0) 0 (0) 0 (0) N/A
  1. For age, disease duration, JADAS-27, ESR, CRP, PLT, ALT and AST, data are presented as median
  2. N/A, not available