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Table 1 Clinical characteristics of sJIA patients and healthy controls

From: Plasma interleukin-37 is increased and inhibits the production of inflammatory cytokines in peripheral blood mononuclear cells in systemic juvenile idiopathic arthritis patients

Characteristics

Active sJIA (n = 23)

Inactiv sJIA (n = 23)

sJIA (n = 46)

HCs (n = 30)

Age (years)

7.3 ± 3.1

7.4 ± 3.3

7.4 ± 3.2

6.6 ± 2.8

Sex, no. F/M

13/10

7/16

20/26

12/18

Disease duration (years)

2.2 ± 0.88

2.0 ± 0.83

2.1 ± 0.86

N/A

JADAS-27

26.09 ± 7.48

13.94 ± 6.82

20.02 ± 9.37

N/A

ESR, mm/h

48.69 ± 5.64

35.77 ± 6.89

41.53 ± 9.69

N/A

CRP, mg/L

25.87 ± 6.17

21.47 ± 3.36

23.7 ± 4.43

N/A

PLT, 109/L

361.39 ± 91.94

350.22 ± 90.98

357.98 ± 90.37

N/A

ALT, U/L

20.07 ± 19.16

24.73 ± 20.72

22.41 ± 19.87

N/A

AST, U/L

33.32 ± 20.00

36.20 ± 18.97

34.76 ± 19.53

N/A

ANA positivity (%)

3 (13.04)

0 (0)

3 (6.52)

N/A

RF positivity (%)

0 (0)

0 (0)

0 (0)

N/A

  1. For age, disease duration, JADAS-27, ESR, CRP, PLT, ALT and AST, data are presented as median
  2. N/A, not available