Fig. 6From: Upregulation of miR-196b-5p attenuates BCG uptake via targeting SOCS3 and activating STAT3 in macrophages from patients with long-term cigarette smoking-related active pulmonary tuberculosismiR-196b-5p inhibited IL-6, TNF-α production on macrophages via activating STAT3 signaling pathway. The supernatant IL-6 (a), TNF-α (b) and IL-10 (c) levels on differentiated U937 cells after exogenously miR-196b-5p, anti-miR-196b-5p transfected were detected by ELISA. And SOCS1, SOCS3, STAT3 and pSTAT3 expression on differentiated U937 cells after exogenously miR-196b-5p, anti-miR-196b-5p transfected were detected by western blotting analysis (d). Data were presented as mean ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001Back to article page