Fig. 3
Immunization with L4.8 evokes CTL activity. Mice were immunized, and cultures were set as mentioned in the legends to Fig. 1. The expression of KLRG1 was monitored on CD4 T cells and CD8 T cells by flow cytometry and represented as: a, b histogram plots; c, d bar diagrams. e, f The lytic ability of CTL was evaluated by in vivo killer T cells assay. The data expressed as target lysis are calculated from the ratio of epitope-pulsed CFSEhi and un-pulsed CFSElo to targets. The results are depicted as mean ± SEM (n = 3 mice/group). *p < 0.05, ****p ≤ 0.0001