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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: A lipidated bi-epitope vaccine comprising of MHC-I and MHC-II binder peptides elicits protective CD4 T cell and CD8 T cell immunity against Mycobacterium tuberculosis

Fig. 3

Immunization with L4.8 evokes CTL activity. Mice were immunized, and cultures were set as mentioned in the legends to Fig. 1. The expression of KLRG1 was monitored on CD4 T cells and CD8 T cells by flow cytometry and represented as: a, b histogram plots; c, d bar diagrams. e, f The lytic ability of CTL was evaluated by in vivo killer T cells assay. The data expressed as target lysis are calculated from the ratio of epitope-pulsed CFSEhi and un-pulsed CFSElo to targets. The results are depicted as mean ± SEM (n = 3 mice/group). *p < 0.05, ****p ≤ 0.0001

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