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Table 5 Univariate Cox regression analysis

From: p53 modeling as a route to mesothelioma patients stratification and novel therapeutic identification

Gene name Beta coefficient Hazard ratio (95% confidence interval for HR) p value
CKB − 0.0621 0.97 (0.819–1.08) 0.376
MUC1 0.181 1.2 (0.944–1.47) 0.0566
FOXM1 0.462 1.59 (1.28–1.96) 1.89E−05
E2F1 0.143 1.15 (1.06–1.25) 0.000551
SFN 0.0768 1.08 (0.983–1.19) 0.111
CKS2 0.408 1.5 (1.19–1.91) 0.000783
CHEK1 0.55 1.73 (1.3–2.31) 0.000165
HSP90AB1 0.494 1.64 (1.25–2.16) 0.000412
RECQL4 0.442 1.56 (1.25–1.94) 8.71E−05
PTTG1 0.397 1.49 (1.18–1.88) 0.000819
AURKA 0.438 1.55 (1.25–1.93) 8.47E−05
PRC1 0.435 1.54 (1.27–1.88) 1.31E−05
HMMR 0.355 1.43 (1.18–1.73) 0.00029
FEN1 0.345 1.41 (1.05–1.91) 0.024
DDIT4 0.348 1.42 (1.16–1.73) 0.000689
MMP2 0.14 1.15 (1.06–1.24) 0.000414
NLRC4 0.109 1.12 (0.844–1.47) 0.443
CDC20 0.361 1.43 (1.21–1.71) 4.61E−05
RAS 0.32 1.38 (1.11–1.71) 0.0039
PLAUR 0.185 1.2 (0.98–1.48) 0.0779
MCTS1 0.542 1.72 (1.09–2.71) 0.0194
GAPDH 0.119 1.13 (0.86–1.47) 0.388
ECT2 0.49 1.63 (1.3–2.04) 1.87E−05
EZH2 0.184 1.2 (1.09–1.33) 0.000268
APAF1 0.443 1.56 (1.15–2.1) 0.00383
BRCA1 0.203 1.22 (1.11–1.35) 6.32E−05
HIF1A 0.146 1.16 (1.01–1.33) 0.0404
MAPK14 0.139 1.15 (0.803–1.64) 0.447
NCL 0.504 1.66 (1.13–2.43) 0.00978
SIAH1 0.143 1.15 (0.974–1.37) 0.0986
  1. The Cox regression results for genes listed in the Table 4 are shown in the Table 5. The column of beta coefficient shows the beta regression coefficient. The column of HR [95% confidence intervals (CI) for HR] list the hazard ratios (the exponentiated coefficients) and the size of the confidence intervals of the hazard ratios. The column of p value lists the p value for the Wald test method