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Table 4 Correlation of genes and processes with survival of mesothelioma patients; the Pearson correlation coefficient is shown

From: p53 modeling as a route to mesothelioma patients stratification and novel therapeutic identification

TP53 WT T

TP53 WT UT

TP53 MUT UT

Gene

Survival correlation

Gene

Survival correlation

Gene

Survival correlation

CKB

0.495

DDIT4

− 0.507

E2F1

− 0.498

MUC1

− 0.510

MMP2

− 0.521

FOXM1

− 0.504

FOXM1

− 0.519

  

NLRC4

− 0.508

E2F1

− 0.526

  

CDC20

− 0.512

SFN

− 0.530

  

AURKA

− 0.515

CKS2

− 0.533

  

RAS

− 0.518

CHEK1

− 0.534

  

PLAUR

− 0.519

HSP90AB1

− 0.535

  

MCTS1

− 0.522

RECQL4

− 0.535

  

GAPDH

− 0.523

PTTG1

− 0.539

  

EZH2

− 0.534

AURKA

− 0.559

  

ECT2

− 0.548

PRC1

− 0.563

  

PRC1

− 0.561

HMMR

− 0.575

  

APAF1

− 0.566

FEN1

− 0.582

  

BRCA1

− 0.579

    

HSP90AB1

− 0.583

    

NCL

− 0.604

    

MAPK14

− 0.611

    

HIF1A

− 0.624

    

SIAH1

− 0.702

  1. Patients treated by chemotherapy are indicated by T; patients untreated by chemotherapy are indicated by UT. Wild type p53 status is labelled WT and mutant is labelled MUT