Skip to main content

Table 4 Correlation of genes and processes with survival of mesothelioma patients; the Pearson correlation coefficient is shown

From: p53 modeling as a route to mesothelioma patients stratification and novel therapeutic identification

TP53 WT T TP53 WT UT TP53 MUT UT
Gene Survival correlation Gene Survival correlation Gene Survival correlation
CKB 0.495 DDIT4 − 0.507 E2F1 − 0.498
MUC1 − 0.510 MMP2 − 0.521 FOXM1 − 0.504
FOXM1 − 0.519    NLRC4 − 0.508
E2F1 − 0.526    CDC20 − 0.512
SFN − 0.530    AURKA − 0.515
CKS2 − 0.533    RAS − 0.518
CHEK1 − 0.534    PLAUR − 0.519
HSP90AB1 − 0.535    MCTS1 − 0.522
RECQL4 − 0.535    GAPDH − 0.523
PTTG1 − 0.539    EZH2 − 0.534
AURKA − 0.559    ECT2 − 0.548
PRC1 − 0.563    PRC1 − 0.561
HMMR − 0.575    APAF1 − 0.566
FEN1 − 0.582    BRCA1 − 0.579
     HSP90AB1 − 0.583
     NCL − 0.604
     MAPK14 − 0.611
     HIF1A − 0.624
     SIAH1 − 0.702
  1. Patients treated by chemotherapy are indicated by T; patients untreated by chemotherapy are indicated by UT. Wild type p53 status is labelled WT and mutant is labelled MUT