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Table 1 The predictive values of clinical features and risk score

From: Systematic analysis of lncRNA–miRNA–mRNA competing endogenous RNA network identifies four-lncRNA signature as a prognostic biomarker for breast cancer

Variables Patients (N) Univariate analysis Multivariate analysis
HR (95% CI) P HR (95% CI) P
Age
 < 60/≥ 60 572/506 1.67 (1.13–2.48) 0.010 2.46 (1.37–4.42) 0.003
Pathologic stage
 I–II/III–IV 799/279 2.47 (1.67-–3.66) 0.000 2.86 (1.15–7.11) 0.024
Stage T
 T1–T2/T3–T4 901/177 1.26 (0.8–1.97) 0.323 1.41 (0.59–3.35) 0.440
Stage N
 N0/NX 512/566 2.56 (1.65–3.95) 0.000 1.12 (0.53–2.37) 0.773
Stage M
 M0/MX 901/177 1.79 (1.05–3.07) 0.034 0.48 (0.17–1.33) 0.156
ER
 Negative/positive 232/796 0.58 (0.38–0.88) 0.011 1.15 (0.31–4.32) 0.837
PR
 Negative/positive 338/687 0.57 (0.38–0.86) 0.007 0.54 (0.2–1.47) 0.226
Her2
 Negative/positive 552/163 2.3 (1.29–4.1) 0.005 2.24 (1.06–4.72) 0.034
Triple negative
 No/yes 598/112 1.59 (0.82–3.07) 0.168 1.69 (0.46–6.19) 0.428
Risk score
 Low/high 593/593 2.16 (1.42–3.29) 0.000 2.26 (1.15–4.43) 0.017
  1. HR hazard ratio, CI confidence interval