Identification of invasion-metastasis-associated microRNAs in hepatocellular carcinoma based on bioinformatic analysis and experimental validation

Table 2 Top ten downregulated differentially expressed miRNAs between HCC tumor with vascular invasion and without vascular invasion

miRNA	Log₂FC	AveExpr	t	P value	adj.P.val	B
hsa-miR-199a-3p	− 3.49273	7.052915	− 13.3399	2.38E−28	2.88E−26	53.79083
hsa-miR-199b-3p	− 3.46525	7.057111	− 13.0789	1.33E−27	1.13E−25	52.08226
hsa-miR-126-3p	− 3.36828	9.212248	− 13.2869	3.38E−28	3.58E−26	53.44345
hsa-miR-195-5p	− 3.19533	7.128742	− 15.3637	4.02E−34	3.41E−31	66.96628
hsa-miR-30a-5p	− 3.14494	7.071084	− 13.2253	5.07E−28	4.78E−26	53.04028
hsa-miR-143-3p	− 3.07332	9.16678	− 11.141	4.62E−22	2.17E−20	39.44342
hsa-miR-100-5p	− 2.90109	8.128079	− 10.7776	4.92E−21	1.90E−19	37.10007
hsa-miR-19b-3p	− 2.87469	7.51099	− 10.8113	3.96E−21	1.60E−19	37.31624
hsa-miR-21-5p	− 2.85469	5.834845	− 14.4948	1.18E−31	3.34E−29	61.33273
hsa-miR-146b-5p	− 2.81179	6.432729	− 10.1073	3.72E−19	1.17E−17	32.81846

ISSN: 1479-5876