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Table 2 Associations between clinicopathologic variables and SII

From: The systemic immune-inflammation index is an independent predictor of survival for metastatic colorectal cancer and its association with the lymphocytic response to the tumor

Characteristics

Mean

s.e.m.

Median

P-value

Age (years)

 < 65

857.17

50.70

637.76

0.36

 ≥ 65

866.76

81.21

697.67

Gender

 Male

898.28

56.40

650.76

0.35

 Female

786.47

63.49

637.76

Histologic grade

 Mod/well differentiated

862.53

49.40

699.31

0.27

 Poorly differentiated

818.38

87.84

585.0

Primary site

 Colon

884.17

47.35

697.67

0.07

 Rectum

737.66

99.95

595.71

 

T-stage

 T1–3

897.49

60.33

675.11

0.55

 T4

784.97

58.11

613.79

LN status

 pN0

933.26

94.50

694.81

0.28

 pN+

827.44

48.37

637.94

MMR status

 dMMR

897.14

195.05

747.13

0.71

 pMMR

857.63

44.17

648.99

Metastatic sites

 Liver

877.09

53.67

668.48

0.43

 Extrahepatic disease

831.49

71.88

639.15

No. of metastatic organs

 Single

797.31

51.82

607.71

0.02

 Multiple

969.17

74.88

775.77

  1. SII systemic immune-inflammation index, LN lymph node