Enrichment score | Gene ontology terms and annotations | Count | p value |
---|---|---|---|
7.08 | Cell–cell adherens junction | 18 | 1.4E−08 |
Cadherin binding involved in cell–cell adhesion | 17 | 2.0E−08 | |
Cell–cell adhesion | 14 | 2.2E−06 | |
5.44 | Tight junction | 10 | 6.6E−08 |
Bicellular tight junction | 10 | 1.4E−06 | |
Tight junction | 9 | 8.1E−06 | |
Bicellular tight junction assembly | 5 | 2.4E−04 | |
4.67 | Pleckstrin homology-like domain | 17 | 2.6E−06 |
Pleckstrin homology domain | 13 | 9.3E−06 | |
Domain: PH | 11 | 8.0E−05 | |
PH | 12 | 1.1E−04 | |
3.35 | SH2 domain | 8 | 9.1E−05 |
Domain: SH2 | 7 | 2.3E−04 | |
SH2 domain | 7 | 3.9E−04 | |
SH2 | 6 | 4.8E−03 | |
3.34 | Glycoprotein | 64 | 6.0E−05 |
Glycosylation site: N-linked (GlcNAc…) | 61 | 1.1E−04 | |
Disulfide bond | 44 | 6.4E−04 | |
Signal peptide | 48 | 9.7E−04 | |
Disulfide bond | 48 | 9.8E−04 | |
Signal | 54 | 2.2E−03 | |
2.76 | Topological domain: cytoplasmic | 53 | 8.1E−05 |
Membrane | 91 | 1.6E−04 | |
Transmembrane region | 66 | 8.5E−04 | |
Topological domain: extracellular | 42 | 9.2E−04 | |
Transmembrane helix | 66 | 7.2E−03 | |
Transmembrane | 66 | 7.7E−03 | |
Integral component of membrane | 59 | 8.4E−02 | |
2.6 | Domain: SH3 | 9 | 1.9E−04 |
SH3 domain | 9 | 6.5E−04 | |
Src homology-3 domain | 8 | 4.4E−03 | |
SH3 | 6 | 6.9E−02 | |
2.48 | Signal peptide | 48 | 9.7E−04 |
Secreted | 31 | 2.0E−03 | |
Extracellular region | 25 | 1.9E−02 | |
2.43 | Establishment of protein localization to plasma membrane | 6 | 4.9E−05 |
Cell adhesion molecule binding | 5 | 3.0E−03 | |
Actin cytoskeleton | 4 | 3.5E−01 | |
2.32 | Extracellular matrix organization | 10 | 1.2E−04 |
Epidermolysis bullosa, junctional, non-Herlitz type | 3 | 2.8E−04 | |
Epidermolysis bullosa | 4 | 2.8E−04 | |
Hemidesmosome assembly | 3 | 5.7E−03 | |
ECM-receptor interaction | 4 | 2.9E−02 | |
Focal adhesion | 5 | 7.2E−02 | |
PI3K-Akt signaling pathway | 4 | 5.0E−01 | |
2.19 | Serine protease | 8 | 2.5E−04 |
Peptidase S1, trypsin family, active site | 7 | 3.9E−04 | |
Domain: peptidase S1 | 7 | 4.7E−04 | |
Active site: charge relay system | 9 | 5.3E−04 | |
Peptidase S1 | 7 | 9.1E−04 | |
Trypsin-like cysteine/serine peptidase domain | 7 | 1.3E−03 | |
Tryp_SPc | 7 | 1.6E−03 | |
Extrinsic component of plasma membrane | 4 | 1.7E−03 | |
Peptidase S1A, chymotrypsin-type | 6 | 4.1E−03 | |
Serine-type endopeptidase activity | 8 | 1.2E−02 | |
Serine-type peptidase activity | 4 | 2.3E−02 | |
Protease | 8 | 2.0E−01 | |
Zymogen | 4 | 2.9E−01 | |
Proteolysis | 7 | 3.5E−01 | |
Hydrolase | 13 | 8.1E−01 | |
1.74 | CP2 transcription factor | 3 | 1.3E−03 |
Region of interest: transcription activation | 3 | 3.5E−03 | |
Chromatin DNA binding | 3 | 1.1E−01 | |
Sequence-specific DNA binding | 8 | 2.3E−01 | |
1.69 | O-glycan processing | 6 | 2.7E−04 |
Glycosphingolipid biosynthesis—lacto and neolacto series | 4 | 9.8E−04 | |
Protein glycosylation | 6 | 4.7E−03 | |
Glycosyltransferase | 7 | 1.8E−02 | |
Topological domain: lumenal | 10 | 2.1E−02 | |
Golgi cisterna membrane | 4 | 3.6E−02 | |
Signal-anchor | 9 | 4.8E−02 | |
Golgi apparatus | 12 | 1.0E−01 | |
Golgi membrane | 9 | 2.0E−01 | |
Metabolic pathways | 9 | 7.5E−01 | |
1.51 | Rho guanyl-nucleotide exchange factor activity | 5 | 6.4E−03 |
Regulation of Rho protein signal transduction | 5 | 7.6E−03 | |
Dbl homology (DH) domain | 4 | 2.9E−02 | |
Domain: DH | 3 | 1.3E−01 | |
RhoGEF | 3 | 1.6E−01 |