Fig. 2
Changes in PET/CT images and histopathological examination of both kidneys after high TBI under microscope. Upper panel, the structure of normal renal tubule and glomeruli; degeneration of tubular cells was observed at dose of 8 Gy; formation of tube casts and degeneration and necrosis of tubular cells were observed at doses at dose of 11 Gy; formation of tube casts and degeneration and necrosis of tubular cells and the inflammatory cells infiltration of the renal interstitium were observed at dose of 14 Gy. Bottom panel. For normal both-kidneys 18F-FDG uptake was diffusive and generally of a low level; 18F-FDG uptake was generally of a low level and exhibited an inhomogeneous distribution at dose of 8 Gy irradiation; 18F-FDG uptake was generally of a high level and exhibited an inhomogeneous distribution at dose of 11 Gy irradiation; 18F-FDG uptake was generally of a higher level and exhibited an inhomogeneous distribution at dose of 14 Gy irradiation (H&E stain, original magnification 10 × 20)