Fig. 5

Metabolite Set Enrichment Analysis using amino acid concentrations. a MPS IIIA vs Control. b MPS IIIB vs Control. c MPS IIIC vs Control. d MPS IIID vs Control. e Venn diagram of the significant pathways retrieved from experimental metabolomics data and in silico systems biology approach from Salazar et al. [37]. The diagram shows two common metabolisms: arginine–proline metabolism and urea cycle. Detailed pathway information is given in Additional file 1: Table S6