Effect of metformin on the survival of patients with ALL who express high levels of the ABCB1 drug resistance gene

Table 2 ALL patients mortality and OR model according to use of metformin

	Refractoriness			Relapse
	OR	(95% CI)	p	OR	(95% CI)	p
Age > 35 years	2.25	0.30–16.63	0.426	3.42	0.49–23.77	0.214
Leukocytes > 30× 10³/mcl	6.00	0.56–63.98	0.137	8.57	0.82–89.04	0.072
Metformin user	0.07	0–1.5	0.091	0.05	0–1.15	0.061
Expression ABCB1 negative or high	7.48	0.36–153.79	0.192	2.91	0.28–30.29	0.896

OR odds ratio, CI confidence interval, ABCB1 ATP binding cassette subfamily B member 1

ISSN: 1479-5876